Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation

   Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages

   Carolin Ulbricht et al.

   Heterogeneity in cytoplasmic calcium concentration alongside B cell activation and differentiation is measured intravitally using an interdisciplinary imaging approach and novel numerical analysis.
2. 1. Immunology and Inflammation
   2. Medicine

   Bacterial-fungal interactions in the neonatal gut influence asthma outcomes later in life

   Rozlyn CT Boutin et al.
3. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo

   Gerald Willimsky et al.
4. 1. Immunology and Inflammation

   Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties

   Jinwei Chai et al.

   The novel cathelicidin cathelicidin-MH was identified from the skin of M. heymonsivogt frog, which protects against lipopolysaccharide- and cecal ligation and puncture-induced sepsis, effectively ameliorates multi-organ pathology, especially in lung.
5. 1. Computational and Systems Biology
   2. Immunology and Inflammation

   Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses

   Stephan Wilmes et al.
6. 1. Immunology and Inflammation
   2. Neuroscience

   Development and characterization of a chronic implant mouse model for vagus nerve stimulation

   Ibrahim T Mughrabi et al.

   Long-term, dose-controlled vagus nerve stimulation (VNS) is feasible in mice using a multi-lab validated implantation procedure, allowing therapeutic testing of VNS in many disease models.
7. 1. Genetics and Genomics
   2. Immunology and Inflammation

   Improving oligo-conjugated antibody signal in multimodal single-cell analysis

   Terkild B Buus et al.

   Oligo-conjugated antibodies are a powerful tool but require thorough optimization to reduce background signal, increase sensitivity, and reduce sequencing costs.
8. 1. Immunology and Inflammation
   2. Neuroscience

   Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

   Alessio Vittorio Colombo et al.

   Experiments in a mouse model for Alzheimer’s disease using germ-free and conventionally housed animals reveal that microbiota-derived short-chain fatty acids promote the deposition of cerebral Aβ plaques.
9. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation

   Philipp Kolb et al.

   Molecular mechanisms reveal that human cytomegalovirus has evolved to deploy two individual glycoproteins working in synergy to efficiently evade antibody-mediated immunity mediated by Fc-gamma receptors.
10. 1. Cell Biology
    2. Immunology and Inflammation

    Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

    Shannon M Walsh et al.