Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    Distinct T-cell receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

    Jasmine Rowell, Ching-In Lau ... Tessa Crompton
    The foetal thymic T-cell receptor (TCR) repertoire is distinct from adult, and it is less governed by MHC-restriction, more closely encoded by genomic sequence with distinct gene-segment usage including 3’TRAV to 5’TRAJ.
    1. Medicine
    2. Immunology and Inflammation

    PD-L1+ Neutrophils mediate Susceptibility during Systemic Inflammatory Response in Non-Alcoholic Fatty Liver Disease

    Cleyson da Cruz Oliveira Barros, Alexandre Kanashiro ... Fernando Queiroz Cunha
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity

    Donal J Cox, Sarah A Connolly ... Joseph Keane
    The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory medicine.
    1. Immunology and Inflammation

    TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

    Nincy Debeuf, Sahine Lameire ... Bart N Lambrecht
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Immunology and Inflammation

    JAK inhibition decreases the autoimmune burden in Down syndrome

    Angela L Rachubinski, Elizabeth Wallace ... Joaquin M Espinosa
    Revised
    Reviewed Preprint v2
    Updated

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Satyajit Rath
    Indian Institute of Science Education and Research (IISER), Pune, India
  3. John W Schoggins
    University of Texas Southwestern Medical Center, United States
  4. See more editors