Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation

   Tight nuclear tethering of cGAS is essential for preventing autoreactivity

   Hannah E Volkman et al.
2. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   An Integrin/MFG-E8 shuttle loads HIV-1 viral like particles onto follicular dendritic cells in mouse lymph node

   Chung Park, John H Kehrl
3. 1. Human Biology and Medicine
   2. Immunology and Inflammation

   Chronic muscle weakness and mitochondrial dysfunction in the absence of sustained atrophy in a preclinical sepsis model

   Allison M Owen et al.

   Sepsis-induced long-term muscle weakness was reproduced using a refined murine model, which was accompanied by mitochondrial dysfunction in the absence of sustained atrophy, suggesting the promise of mitochondria-targeted post-sepsis therapies.
4. 1. Immunology and Inflammation
   2. Neuroscience

   Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

   Carolyn M Walsh et al.

   Neutrophils are essential for itch in a mouse model of atopic dermatitis, and promote the transition from acute to chronic itch via induction of CXCL10/CXCR3 signaling.
5. 1. Immunology and Inflammation
   2. Neuroscience

   Intestinal infection regulates behavior and learning via neuroendocrine signaling

   Jogender Singh, Alejandro Aballay

   Feedback from the intestine during infection can modulate the behavior, learning, and microbial perception of the host.
6. 1. Immunology and Inflammation
   2. Neuroscience

   Autoimmunity: Bringing on the itch

   Daniel A Waizman et al.

   Neutrophils are the first immune cells that enter the skin and cause itch in atopic dermatitis.
7. 1. Immunology and Inflammation

   Kinetics of cytokine receptor trafficking determine signaling and functional selectivity

   Jonathan Martinez-Fabregas et al.
8. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist

   Kevin W Ng et al.

   An ancient integration of an endogenous retroelement in the gene encoding PD-L1 is exapted to generate a soluble form that antagonises the suppressive function of the membrane-bound form.
9. 1. Immunology and Inflammation

   Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

   Gabriela Krejčová et al.

   Activated Drosophila macrophages undergo transient metabolic remodeling towards Hypoxia inducible factor 1 α-driven aerobic glycolysis, a program that induces systemic metabolic changes and is crucial for resistance to infection.
10. 1. Immunology and Inflammation

    Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4⁺ T cell memory

    Thea Hogan et al.