Immunology and Inflammation

Latest articles

1. 1. Cell Biology
   2. Immunology and Inflammation

   Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells

   Moosung Lee et al.

   Rapid, label-free, volumetric, and automated assessment of the immunological synapse dynamics is demonstrated by combining optical diffraction tomography and deep-learning-based segmentation, providing a new option for immunological research.
2. 1. Immunology and Inflammation

   Cytomegalovirus restricts ICOSL expression on antigen presenting cells disabling T cell co-stimulation and contributing to immune evasion

   Guillem Angulo et al.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Immunocompetent mouse model for Crimean-Congo hemorrhagic fever virus

   David W Hawman et al.

   A mouse-adapted strain of Crimean-Congo hemorrhagic fever virus that recapitulates human disease in wild-type mice significantly improves our ability to study Crimean-Congo hemorrhagic fever virus pathogenesis.
4. 1. Immunology and Inflammation
   2. Medicine

   The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline

   Danielle Janosevic et al.

   Single-cell RNA-sequencing identifies the precise cellular and molecular events that occur along the sepsis timeline in the kidney, pointing to potential biomarkers and therapeutic targets.
5. 1. Immunology and Inflammation
   2. Medicine

   Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2

   Kelsey E Huntington et al.
6. 1. Computational and Systems Biology
   2. Immunology and Inflammation

   Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection

   Anastasia A Minervina et al.

   Longitudinal tracking of individual T-cell clones reveals the expansion of pre-existing T-cell memory in response to SARS-CoV-2 infection.
7. 1. Immunology and Inflammation

   Thymic stromal lymphopoietin limits primary and recall CD8⁺ T-cell anti-viral responses

   Risa Ebina-Shibuya et al.

   Immunological analysis of wild-type and Crlf2^-/- mice reveals a role for the cytokine thymic stromal lymphopoietin on memory CD8⁺ T-cell responses to viral infection, findings with potential translational implications.
8. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post HIV Env trimer vaccination

   Adam S Dingens et al.
9. 1. Immunology and Inflammation

   The clonal structure and dynamics of the human T cell response to an organic chemical hapten

   Tahel Ronel et al.
10. 1. Immunology and Inflammation

    Stochastic asymmetric repartition of lytic machinery in dividing CD8⁺ T cells generates heterogeneous killing behavior

    Fanny Lafouresse et al.