Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine
    2. Immunology and Inflammation

    Complement 3a Receptor 1 on Macrophages and Kupffer cells is not required for the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease

    Edwin A Homan, Ankit Gilani ... James C Lo
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Immunology and Inflammation

    Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

    Ole Bæk, Tik Muk ... Duc Ninh Nguyen
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation

    Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases

    Shih-Wen Huang, Yein-Gei Lai ... Nan-Shih Liao
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation

    Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity

    Donal J Cox, Sarah A Connolly ... Joseph Keane
    The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory medicine.
    1. Immunology and Inflammation

    TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

    Nincy Debeuf, Sahine Lameire ... Bart N Lambrecht
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Immunology and Inflammation

    JAK inhibition decreases the autoimmune burden in Down syndrome

    Angela L Rachubinski, Elizabeth Wallace ... Joaquin M Espinosa
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

    Alisa Sukhina, Clemence Queriault ... Will Bailis
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    Single-Cell and Spatial Transcriptomic Analyses Reveals the Dynamic Transcript Profiles of Myocardial Lymphangiogenesis post Myocardial Infarction

    Jiaqi He, Dali Zhang ... Yaling Han
    Revised
    Reviewed Preprint v3
    Updated
    1. Immunology and Inflammation

    Adipocyte microRNA-802 promotes adipose tissue inflammation and insulin resistance by modulating macrophages in obesity

    Yue Yang, Bin Huang ... Fangfang Zhang
    1. Immunology and Inflammation

    T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type 1 cells

    Josep Garnica, Patricia Sole ... Pere Santamaria
    T-regulatory type 1 cells inherit a broad repertoire of epigenetic marks from T-follicular helper T-cells, offering new insights into the developmental biology of this subset.
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Highlights

    1. Immunology and Inflammation

    Tracking type 1 regulatory T cells

    David P Turicek, Xiaoxiao Wan
    1. Developmental Biology
    2. Immunology and Inflammation

    A hemocyte atlas for an insect

    Samuel Liegeois, Dominique Ferrandon
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  3. Diane M Harper
    University of Michigan, United States
  4. See more editors