Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation

   De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness

   Jaemoon Koh, Yeon Duk Woo ... Doo Hyun Chung
2. 1. Immunology and Inflammation

   Mouse gingival single-cell transcriptomic atlas: An activated fibroblast subpopulation guides oral barrier immunity in periodontitis

   Takeru Kondo, Annie Gleason ... Ichiro Nishimura
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli

   Sharon A McGrath-Morrow, Jarrett Venezia ... Alan L Scott
4. 1. Immunology and Inflammation

   CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance

   Yu Li, Pablo Guaman Tipan ... Lauren IR Ehrlich
5. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

   Minato Hirano, Gaddiel Galarza-Muñoz ... Mariano A Garcia-Blanco

   RNA processing regulates gene expression of the key transcription factor FOXP3 in T regulatory cells impacting immune tolerance and susceptibility to autoimmune disease.
6. 1. Immunology and Inflammation

   Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling

   Rafaela Mano Guimarães, Conceição Elidianne Aníbal-Silva ... Thiago Mattar Cunha
7. 1. Immunology and Inflammation

   Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy

   Pedro P Cunha, Eleanor Minogue ... Randall S Johnson

   Oxygen levels at the time of T cell activation are major determinants of function, even when T cells are subsequently expanded in high levels of oxygen.
8. 1. Immunology and Inflammation

   Maternal group 2 innate lymphoid cells contribute to fetal growth and protection from endotoxin-induced abortion in mice

   Elisa Balmas, Batika MJ Rana ... Francesco Colucci
9. 1. Immunology and Inflammation

   Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

   Sindhu Mohandas, Prasanna Jagannathan ... RECOVER Mechanistic Pathways Task Force

   Immune dysregulation is thought to be a hallmark of long COVID or PASC but there is a need for understanding the underlying mechanisms which drive the disease progression.
10. 1. Computational and Systems Biology
    2. Immunology and Inflammation

    Statistical inference reveals the role of length, GC content, and local sequence in V(D)J nucleotide trimming

    Magdalena L Russell, Noah Simon ... Frederick A Matsen IV

    Local sequence context, length, and GC nucleotide content in both directions of the trimming site, together, are highly predictive of V(D)J trimming probabilities for both TR and IG adaptive immune receptor loci.