Immunology and Inflammation

Immunology and Inflammation

eLife publishes research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    Glutamine metabolism modulates chondrocyte inflammatory response

    Manoj Arra et al.
    Glutamine deprivation reprograms chondrocytes, attenuates inflammation, and such intervention may be protective against joint inflammation.
    1. Immunology and Inflammation

    Natural killer (NK) cell-derived extracellular-vesicle shuttled microRNAs control T cell responses

    Sara G Dosil et al.
    Extracellular vesicles derived from natural killer cells contain a specific repertoire of microRNAs that promote Th1 responses.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14

    Kathrin Tomasek et al.
    By binding with their type 1 pili to the cell surface receptor CD14, pathogenic E. coli suppress the capacity of dendritic cells to activate T cells.
    1. Immunology and Inflammation

    Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition

    Thandeka Nkosi et al.
    Cross-reactive T cell immunity against the SARS-CoV-2 is severely compromised in HIV viremic individual.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Towards a unified model of naive T cell dynamics across the lifespan

    Sanket Rane et al.
    Naive CD4 and CD8 T cells in mice increase their survival capacity with age, but their numbers are not homeostatically regulated.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Adaptive Immunity: Maintaining naivety of T cells

    Ken Duffy
    Mathematical models encoding biological hypotheses reveal new insight into the dynamics of naive immune cells in mice from birth to old age.
    Insight
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Senior editors

  1. Arturo Casadevall
    Johns Hopkins Bloomberg School of Public Health, United States
  2. Miles P Davenport
    University of New South Wales, Australia
  3. Diane M Harper
    University of Michigan, United States
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