Immunology and Inflammation

Latest articles

1. 1. Computational and Systems Biology
   2. Immunology and Inflammation

   An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans

   Murilo Delgobo et al.
2. 1. Immunology and Inflammation
   2. Neuroscience

   Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

   Carolyn M Walsh et al.
3. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements

   Michel Tassetto et al.

   Virus infection in mosquitoes initiates a highly discriminatory process in which fragments of viral RNA are reverse transcribed to create DNA copies that serve as templates of small antiviral RNAs.
4. 1. Immunology and Inflammation

   Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation

   Atiqur Rahman et al.
5. 1. Immunology and Inflammation

   Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

   Gabriela Krejčová et al.
6. 1. Immunology and Inflammation

   Natural Tr1-like cells do not confer long-term tolerogenic memory

   Koshika Yadava et al.

   Natural Tr1-like cells do not form a functionally stable memory response to allergens, and this instability may limit efforts to re-establish tolerance by expanding Tr1.
7. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Complement and CD4⁺ T cells drive context-specific corneal sensory neuropathy

   Derek J Royer et al.

   The complement pathway can contribute to corneal sensation loss and nerve damage during ocular surface inflammation.
8. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Neuropathy: Looking into nerve damage in the cornea

   Mihaela Gadjeva

   Interactions between T helper cells and the complement system promote loss of sensory neurons in the eye.
9. 1. Immunology and Inflammation

   High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node

   Szandor Simmons et al.

   Impairment of the autocrine S1PR1-Gi signaling on HEVs results in high-endothelial cell apoptosis, reduced CCL21-secretion from HEVs, and cessation of HEV-DC interactions and lymphocyte immigration across the high-endothelial barrier.
10. 1. Human Biology and Medicine
    2. Immunology and Inflammation

    ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis

    Thomas Scambler et al.

    Dysfunction and overexpression of ENaC-mediated sodium influx exacerbates activation of NLRP3-inflammasome mediated inflammation in cells with CF-associated mutations and is modulated by inhibition of these amiloride-sensitive sodium (Na⁺) channels.