Immunology and Inflammation

Immunology and Inflammation

eLife publishes research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we publish and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2

    Oksana Tsyklauri, Tereza Chadimova ... Ondrej Stepanek
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A hierarchy of cell death pathways confers layered resistance to shigellosis in mice

    Justin L Roncaioli, Janet Peace Babirye ... Russell E Vance
    Genetic analyses using a new oral infection mouse model demonstrate that cell death pathways protect against the gastrointestinal bacterial pathogen Shigella flexneri.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling

    Anastasia O Smirnova, Anna M Miroshnichenkova ... Alexander Komkov
    1. Immunology and Inflammation

    Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis

    Gerdien Mijnheer, Nila Hendrika Servaas ... Femke van Wijk
    1. Immunology and Inflammation
    2. Physics of Living Systems

    Quantifying changes in the T cell receptor repertoire during thymic development

    Francesco Camaglia, Arie Ryvkin ... Nir Friedman
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Structure-based prediction of T cell receptor:peptide-MHC interactions

    Philip Bradley
    The AlphaFold protein structure prediction network can be specialized for T cell receptor docking, leading to improved models of ternary complexes and some ability to discriminate correct from incorrect peptide epitopes.
    1. Immunology and Inflammation

    T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance

    Xin Gao, Kaiming Luo ... Di Yu
    1. Immunology and Inflammation
    2. Medicine

    FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

    Cong Liu, Milena Schönke ... Patrick CN Rensen
    1. Cell Biology
    2. Immunology and Inflammation

    Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10

    Ana J Caetano, Yushi Redhead ... Paul T Sharpe
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent

    Klara M Wanelik, Mike Begon ... Steve Paterson
    Genetic variation can have multiple effects on different phenotypic traits in organisms living in the natural environment.
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Senior editors

  1. Arturo Casadevall
    Johns Hopkins Bloomberg School of Public Health, United States
  2. Miles P Davenport
    University of New South Wales, Australia
  3. Tadatsugu Taniguchi
    Tadatsugu Taniguchi
    Research Center for Advanced Science and Technology, The University of Tokyo, Japan
  4. See more editors