Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes

    Tiantian Kou, Lan Kang ... Xiaoyu Hu
    Experiments including cell and animal models investigate the molecular mechanisms underlying the regulation of homeostasis and function of monocytes.
    1. Immunology and Inflammation

    Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

    Preksha Gaur, Yesheswini Rajendran ... Chittur V Srikanth
    1. Cell Biology
    2. Immunology and Inflammation

    Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells

    Chinky Shiu Chen Liu, Tithi Mandal ... Dipyaman Ganguly
    A hitherto unknown role of Piezo1 mechanosensors in chemotactic migration of human T cells is identified, linking focal adhesion formation to integrin recruitment.
    1. Immunology and Inflammation

    Tailoring Tfh profiles enhances antibody persistence to a clade C HIV-1 vaccine in rhesus macaques

    Anil Verma, Chase E Hawes ... Smita S Iyer
    Strategies to enhance Tfh cells for HIV-vaccine antibody persistence and protection is pivotal for vaccine success.
    1. Cell Biology
    2. Immunology and Inflammation

    NAD+ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages

    Jasper Iske, Rachid El Fatimy ... Abdallah Elkhal
    NAD+ exhibits profound therapeutic effects in experimental septic shock models by dampening the systemic inflammatory response and leading to improved survival.

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  3. Diane M Harper
    University of Michigan, United States
  4. See more editors