Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    PIM kinase control of CD8 T cell protein synthesis and cell trafficking

    Julia M Marchingo, Laura Spinelli ... Doreen A Cantrell
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation

    β-glucan reprograms alveolar macrophages via neutrophil/IFNγ axis to promote lung injury

    Renaud Prével, Erwan Pernet ... Maziar Divangahi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein

    Kentarou Waki, Hideki Tani ... Nobuyuki Kurosawa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

    Yuanyuan Xu, Qipeng ... Xinsheng Yao
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    Re-programming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation

    Israel Ríos, Cristina Herrero ... Ángel L Corbí
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Immunology and Inflammation

    RAG suppresses group 2 innate lymphoid cells

    Aaron M Ver Heul, Madison Mack ... Brian S Kim
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

    Jeremy M Shea, Saul A Villeda
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A modular platform to display multiple hemagglutinin subtypes on a single immunogen

    Dana Thornlow Lamson, Faez Amokrane Nait Mohamed ... Aaron G Schmidt
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    The extra-islet pancreas supports autoimmunity in human type 1 diabetes

    Graham L Barlow, Christian M Schürch ... Paul L Bollyky
    A high-parameter, spatial analysis of the pancreata of individuals with type 1 diabetes reveals specific patterns of immune infiltration into islets of Langerhans, coordinated with changes in the surrounding tissue.
    1. Immunology and Inflammation

    Coevolutionary interplay: Helminths-trained immunity and its impact on the rise of inflammatory diseases

    Eugenio Antonio Carrera Silva, Juliana Puyssegur, Andrea Emilse Errasti
    Deciphering the gut biome's, including helminths', influence on human trained immunity will unlock novel immunotherapies harnessing the immune reprogramming potential of their secreted factors and extracellular vesicles.
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Highlights

    1. Developmental Biology
    2. Immunology and Inflammation

    A hemocyte atlas for an insect

    Samuel Liegeois, Dominique Ferrandon
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Parkinson's and innate immunity

    Rebecca L Wallings, Mary K Herrick, Malú Gámez Tansey

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  3. Diane M Harper
    University of Michigan, United States
  4. See more editors