Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Medicine
    2. Immunology and Inflammation

    NK Cell Exhaustion in Wilson’s Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis

    Yong Jin, Jiayu Xing ... Qingsheng Yu
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation

    Distinct T-cell receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

    Jasmine Rowell, Ching-In Lau ... Tessa Crompton
    The foetal thymic T-cell receptor (TCR) repertoire is distinct from adult, and it is less governed by MHC-restriction, more closely encoded by genomic sequence with distinct gene-segment usage including 3’TRAV to 5’TRAJ.
    1. Medicine
    2. Immunology and Inflammation

    PD-L1+ Neutrophils mediate Susceptibility during Systemic Inflammatory Response in Non-Alcoholic Fatty Liver Disease

    Cleyson da Cruz Oliveira Barros, Alexandre Kanashiro ... Fernando Queiroz Cunha
    Not revised
    Reviewed Preprint v1
    1. Medicine
    2. Immunology and Inflammation

    Complement 3a Receptor 1 on Macrophages and Kupffer cells is not required for the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease

    Edwin A Homan, Ankit Gilani ... James C Lo
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Immunology and Inflammation

    Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

    Ole Bæk, Tik Muk ... Duc Ninh Nguyen
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation

    Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases

    Shih-Wen Huang, Yein-Gei Lai ... Nan-Shih Liao
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation

    Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity

    Donal J Cox, Sarah A Connolly ... Joseph Keane
    The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory medicine.
    1. Immunology and Inflammation

    TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

    Nincy Debeuf, Sahine Lameire ... Bart N Lambrecht
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Immunology and Inflammation

    JAK inhibition decreases the autoimmune burden in Down syndrome

    Angela L Rachubinski, Elizabeth Wallace ... Joaquin M Espinosa
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

    Alisa Sukhina, Clemence Queriault ... Will Bailis
    Not revised
    Reviewed Preprint v1
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Highlights

    1. Immunology and Inflammation

    Tracking type 1 regulatory T cells

    David P Turicek, Xiaoxiao Wan
    1. Developmental Biology
    2. Immunology and Inflammation

    A hemocyte atlas for an insect

    Samuel Liegeois, Dominique Ferrandon
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Satyajit Rath
    Indian Institute of Science Education and Research (IISER), Pune, India
  3. John W Schoggins
    University of Texas Southwestern Medical Center, United States
  4. See more editors