Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

    Yuanyuan Xu, Qi Peng ... Xinsheng Yao
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

    Esther Liu, Matthew Wright ... Jennie Lin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Correlates of protection against African swine fever virus identified by a systems immunology approach

    Kirill Lotonin, Francisco Brito ... Artur Summerfield
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Thrifty wide-context models of B cell receptor somatic hypermutation

    Kevin Sung, Mackenzie M Johnson ... Frederick A Matsen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Immunology and Inflammation

    Cap-independent co-expression of dsRNA-sensing and NF-κB pathway inhibitors enables tunable self-amplifying RNA expression with reduced immunotoxicity

    Tony KY Lim, Anne Ritoux ... Ewan St. John Smith
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophages

    Upneet K Sokhi, Ruoxi Yuan ... Lionel B Ivashkiv
    Interferon-γ and prostaglandin E2 signaling oppose each other to determine the balance between two distinct TNF-induced inflammatory gene expression programs relevant for rheumatoid and immune checkpoint inhibitor-induced arthritis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

    Alisa Sukhina, Clemence Queriault ... Will Bailis
    Dysregulated myelopoiesis is identified as a driver of nutritionally acquired immunodeficiency that persists after refeeding and nutritional recovery, indicating exposure to food scarcity may be an immunologic risk factor.
    1. Medicine
    2. Immunology and Inflammation

    A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies

    Thomas Balligand, Claire Carpenet ... Maarten Dewilde
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Glycosylated IgG antibodies accelerated the recovery of haemorrhagic fever with renal syndrome patients

    Chuansong Quan, Lu Wang ... Haifeng Hou
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    Coenzyme A governs proinflammatory macrophage metabolism

    Greg. A Timblin, Kevin. M Tharp ... Valerie M Weaver
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
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Highlights

    1. Immunology and Inflammation

    The double-edged nature of trained immunity

    Chrissy M Leopold Wager, Larry S Schlesinger
    1. Developmental Biology
    2. Immunology and Inflammation

    A hemocyte atlas for an insect

    Samuel Liegeois, Dominique Ferrandon
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Diane M Harper
    University of Michigan, United States
  3. Tony Ng
    King's College London, United Kingdom
  4. See more editors