Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation

   A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

   Yuji Miyatake, Takeshi Kamakura ... Ai Kotani
2. 1. Immunology and Inflammation

   A co-evolutionary perspective on humans and Mycobacterium tuberculosis in the era of systems biology

   Michaela T Reichmann, Liku B Tezera ... Paul T Elkington

   The deep evolutionary relationship between humans and Mycobacterium tuberculosis suggests latent infection may confer benefit, with important consequences for investigating and interpreting host–pathogen interactions.
3. 1. Immunology and Inflammation
   2. Evolutionary Biology

   Separating selection from mutation in antibody language models

   Frederick A Matsen, Will Dumm ... Hugh K Haddox
4. 1. Immunology and Inflammation

   Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs

   Gagandeep Kaur, Thomas Lamb ... Irfan Rahman
5. 1. Cell Biology
   2. Immunology and Inflammation

   Male-Biased Cyp17a2 Orchestrates Antiviral Sexual Dimorphism in Fish via STING Stabilization and Viral Protein Degradation

   Long-Feng Lu, Bao-jie Cui ... Shun Li
6. 1. Immunology and Inflammation

   Epidermal resident memory T cell fitness requires antigen encounter in the skin

   Eric S Weiss, Toshiro Hirai ... Daniel H Kaplan

   Antigen-driven TCR signaling in the epidermis during CD8⁺ T_RM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal T_RM fitness.
7. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Glycosylated IgG antibodies contribute to the recovery of haemorrhagic fever with renal syndrome patients

   Chuansong Quan, Lu Wang ... Haifeng Hou

   Increased fucosylated IgG and reduced bisecting GlcNAc during HTNV convalescence may promote rapid recovery from hemorrhagic fever with renal syndrome.
8. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Phospholipid scramblase 1 (PLSCR1) regulates interferon-lambda receptor 1 (IFN-λR1) and IFN-λ signaling in influenza A virus (IAV) infection

   Alina Xiaoyu Yang, Lisa Ramos-Rodriguez ... Yang Zhou

   PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.
9. 1. Immunology and Inflammation

   Class A scavenger receptor MARCO negatively regulates Ace expression and aldosterone production

   Conan JO O'Brien, Giorgio Ratti ... Ana I Domingos

   Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.
10. 1. Immunology and Inflammation

    Trained Immunity: RoadMap for drug discovery and development

    Jelmer H van Puffelen, Callum Campbell ... Pauline T Lukey

    Combining scientific rigour and drug development experience to map out a route to novel treatments for Trained Immunity-dependent diseases.