Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation

    Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived stem cell factor

    Chenchen Mao, Yanyu Chen ... Xiangyang Xue
    Resting natural killer cells promote the progress of colon cancer liver metastasis (CCLM), which may be exploited for novel strategies to improve therapeutic outcomes for patients with CCLM.
    1. Immunology and Inflammation
    2. Neuroscience

    Transcriptional responses in a mouse model of silicone wire embolization induced acute retinal artery ischemia and reperfusion

    Yuedan Wang, Ying Li ... Xuan Xiao
    The UPOAO model effectively replicates retinal ischemia in retinal artery occlusion, providing a novel platform for identifying pathogenic genes and advancing therapeutic research.
    1. Immunology and Inflammation

    PD-1 negatively regulates helper T cell differentiation into Th2

    Masaki Tajima, Naoko Ikuta ... Akio Ohta
    1. Immunology and Inflammation

    LPS-induced systemic inflammation is suppressed by the PDZ motif peptide of ZO-1 via regulation of macrophage M1/M2 polarization

    Hyun-Chae Lee, Sun-Hee Park ... Kyoung Seob Song
    PEGylated PDZ peptide reduces LPS-induced systemic inflammation, restores tissue integrity, decreases pro-inflammatory cytokines, and modulates macrophage populations, showing potential as a therapeutic for systemic inflammation.
    1. Cancer Biology
    2. Immunology and Inflammation

    A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets

    Akashdip Singh, Alberto Miranda Bedate ... Linde Meyaard
    A bioinformatics pipeline describes 390 putative, novel inhibitory receptors, to facilitate targeted therapeutic strategies for diverse immune cell types in cancer therapy.

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  3. Diane M Harper
    University of Michigan, United States
  4. See more editors