Immunology and Inflammation

Latest articles

1. 1. Immunology and Inflammation
   2. Medicine

   Expansion of CD10^neg neutrophils and CD14⁺HLA-DR^neg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction

   Daniela Fraccarollo et al.

   Immature CD10^neg neutrophils and CD14⁺HLA-DR^neg/low monocytes inducing proinflammatory and adaptive immune responses emerge in patients with large acute myocardial infarction.
2. 1. Genetics and Genomics
   2. Immunology and Inflammation

   Single-cell analysis of mosquito hemocytes identifies signatures of immune cell sub-types and cell differentiation

   Hyeogsun Kwon et al.
3. 1. Developmental Biology
   2. Immunology and Inflammation

   Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

   Xia Liu et al.

   Endoplasmic reticulum-associated degradation (ERAD) is a critical protein quality control checkpoint for thymocyte β-slection.
4. 1. Cell Biology
   2. Immunology and Inflammation

   RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination

   Ziwei Yang et al.

   RTN3 is upregulated upon RNA viral infection, in turn suppresses antiviral responses by impairing TRIM25-mediated RIG-I K63-linked polyubiquitination and decreases neutrophil populations and inflammatory infiltration, representing a novel inflammatory resolution.
5. 1. Immunology and Inflammation
   2. Physics of Living Systems

   T cell stiffness is enhanced upon formation of immunological synapse

   Philipp Jung et al.
6. 1. Immunology and Inflammation

   Pioneer neutrophils release chromatin within in vivo swarms

   Hannah M Isles et al.

   Neutrophil swarms form around a single endogenous pioneer neutrophil in vivo, mediated by DNA release from pioneer neutrophils.
7. 1. Computational and Systems Biology
   2. Immunology and Inflammation

   Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

   Margaret A Myers et al.
8. 1. Genetics and Genomics
   2. Immunology and Inflammation

   Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2

   Elektra K Robinson et al.

   Alternative first exon usage was the major event observed in macrophages during inflammation, which resulted in the elucidation of a novel isoform and regulatory mechanism of the protein-coding gene, Aim2.
9. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   Method development and characterisation of the low-molecular-weight peptidome of human wound fluids

   Mariena JA van der Plas et al.

   Peptidomics method development and analysis of qualitative differences of peptide patterns in human wound fluids provide potential biomarkers for wound healing and infection.
10. 1. Immunology and Inflammation
    2. Medicine

    Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

    Dongjin Jeong et al.

    Soluble Fas ligand interacts specifically with tumor necrosis factor receptor superfamily (TNFRSF)10B, also known as death receptor 5, exacerbating arthritis in a Fas-independent manner.