Immunology and Inflammation

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   N-chlorination mediates protective and immunomodulatory effects of oxidized human plasma proteins

   Agnes Ulfig et al.

   N-chlorination, a reversible, oxidative modification, turns plasma proteins into holdase-like chaperones, potent activators of immune cells and pro-survival factors for phagocytic immune cells.
2. 1. Immunology and Inflammation

   The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets

   Takuya Koike et al.

   Unveiling a mechanism for the fate decision of B-cell differentiation into two functionally distinct memory B cell subsets.
3. 1. Immunology and Inflammation

   Conformational change within the extracellular domain of B cell receptor in B cell activation upon antigen binding

   Zhixun Shen et al.

   Conformational changes occur within extracellular domain of BCR upon antigen engagement, and these conformational changes are related with the strength of BCR activation and are distinct in IgM- and IgG-BCR.
4. 1. Cell Biology
   2. Immunology and Inflammation

   Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

   Junghyun Lim et al.

   Autophagy is critical for the turnover of inflammatory signaling complexes containing RHIM-domain proteins.
5. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides

   Mattia Ficarelli et al.

   KHNYN, a putative endoribonuclease, interacts with the zinc-finger antiviral protein (ZAP) and is required for the inhibition of HIV replication and RNA abundance by CpG dinucleotides.
6. 1. Biochemistry and Chemical Biology
   2. Immunology and Inflammation

   Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells

   Ben F Brian et al.
7. 1. Immunology and Inflammation
   2. Microbiology and Infectious Disease

   Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity

   Nathella Pavan Kumar et al.
8. 1. Human Biology and Medicine
   2. Immunology and Inflammation

   Response to comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

   Christina Hertel et al.

   We are writing to reply to the comment by Landegren et al., 2019 about our study (Meyer et al., 2016) on disease-ameliorating autoantibodies.
9. 1. Human Biology and Medicine
   2. Immunology and Inflammation

   Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

   Nils Landegren et al.

   We are writing to comment on the study by Meyer et al., 2016 on disease-ameliorating autoantibodies.
10. 1. Immunology and Inflammation

    Circulating T cell-monocyte complexes are markers of immune perturbations

    Julie G Burel et al.

    Human blood contains T cell-monocyte complexes which are not technical artefacts but reflect true in vivo immune cell interactions.