TGGT1_268210 | AGC kinase | SPARK | | Smith et al., 2022 | |
TGGT1_291010 | hypothetical protein | SPARKEL | | | SPARK IP-MS |
TGGT1_205550 | AGC kinase | AGC kinase | | | SPARK TurboID, SPARKEL TurboID |
TGGT1_310220 | hypothetical protein | BCC10 | | Engelberg et al., 2022 | SPARKEL IP-MS |
TGGT1_269460 | Ser/Thr phosphatase family protein | EFPP/BCC5 | S550 | Engelberg et al., 2022; Liang et al., 2021; Roumégous et al., 2022 | SPARKEL IP-MS, SPARK depletion timecourse phosphoproteome |
TGGT1_311360 | protein kinase G AGC kinase family member PKG | PKG | | Brown et al., 2017 | 24 hr SPARK depletion proteome, SPARK depletion timecourse phosphoproteome |
TGGT1_226030 | AGC kinase | PKA C1 | | Jia et al., 2017; Uboldi et al., 2018 | 24 hr SPARK depletion proteome, SPARK depletion timecourse phosphoproteome |
TGGT1_242070 | cAMP-dependent protein kinase regulatory subunit | PKA R | S27 | Jia et al., 2017; Uboldi et al., 2018 | 24 hr SPARK depletion proteome, SPARK depletion timecourse phosphoproteome, PKA C3 depletion proteome |
TGGT1_270240 | MAG1 protein | MAG1 | S238 | Parmley et al., 1994 | 24 hr SPARK depletion proteome, PKA C3 depletion phosphoproteome |
TGGT1_314250 | bradyzoite rhoptry protein | BRP1 | | Schwarz et al., 2005 | 24 hr SPARK depletion proteome, 24 hr PKA C3 depletion proteome |
TGGT1_208740 | putative microneme protein | | | Waldman et al., 2020 | 24 hr SPARK depletion proteome, 24 hr PKA C3 depletion proteome |
TGGT1_264660 | SAG-related sequence SRS44 | CST1 | | Tomita et al., 2013 | 24 hr SPARK depletion proteome, PKA C3 depletion transcriptome |
TGGT1_312330 | hypothetical protein | CST10 | | Tu et al., 2020; Waldman et al., 2020 | 24 hr SPARK depletion proteome, PKA C3 depletion transcriptome |
TGGT1_260190 | microneme protein MIC13 | MIC13 | | Fritz et al., 2012 | 24 hr SPARK depletion proteome, PKA C3 depletion transcriptome |
TGGT1_311100 | zinc finger (CCCH type) motif-containing protein | BFD2 | S183 | Licon et al., 2023 | 24 hr SPARK depletion proteome, 24 hr PKA C3 depletion proteome, PKA C3 depletion phosphoproteome |
TGGT1_266010 | phosphatidylinositol 3- and 4-kinase | PI3/4 K | S1439 | | SPARK depletion timecourse phosphoproteome |
TGGT1_202550 | NLI interacting factor family phosphatase | CTD3/BCC6 | T384 and T386 | Engelberg et al., 2022 | SPARK depletion timecourse phosphoproteome |
TGGT1_224240 | protein phosphatase 2 C domain-containing protein | PPM1 | S557 | Yang and Arrizabalaga, 2017 | SPARK depletion timecourse phosphoproteome |
TGGT1_268770 | dual specificity phosphatase, catalytic domain-containing protein | phosphosite down-regulated with SPARK depletion | S11 | | SPARK depletion timecourse phosphoproteome |
TGGT1_219682 | putative pyruvate dehydrogenase kinase | | S633 | Ferrarini et al., 2021 | SPARK depletion timecourse phosphoproteome |
TGGT1_225960 | STE kinase | | S2905 | | SPARK depletion timecourse phosphoproteome |
TGGT1_305860 | calcium-dependent protein kinase 3 | CDPK3 | T40 | | SPARK depletion timecourse phosphoproteome |
TGGT1_267580 | cyclin2-related protein | | S491 | | SPARK depletion timecourse phosphoproteome |
TGGT1_204280 | cell-cycle-associated protein kinase DYRK | | T642, S645, and S649 | Smith et al., 2022 | SPARK depletion timecourse phosphoproteome |
TGGT1_239885 | hypothetical protein | | S933 and S936 | Smith et al., 2022 | SPARK depletion timecourse phosphoproteome |
TGGT1_267100 | protein phosphatase 2 C domain-containing protein | PPM2B | S/T778-788 | Yang et al., 2019 | SPARK depletion timecourse phosphoproteome |
TGGT1_311310 | protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein | CnA | S104 | Paul et al., 2015 | SPARK depletion timecourse phosphoproteome |
TGGT1_277895 | ubiquitin carboxyl-terminal hydrolase | UBP1 | S44, S52, S1691, and S1695 | Koreny et al., 2023; Wan et al., 2023 | SPARK depletion timecourse phosphoproteome |
TGGT1_294360 | putative ubiquitin specific protease 39 isoform 2 | USP39 | S20 | | SPARK depletion timecourse phosphoproteome |
TGGT1_226050 | hypothetical protein | RBR E3 ligase | S319 and S322 | | SPARK depletion timecourse phosphoproteome |
TGGT1_239410 | hypothetical protein | putative CCR4-NOT complex subunit | S80 | | SPARK depletion timecourse phosphoproteome |
TGGT1_295658 | zinc finger in N-recognin protein | UBR box E3 ligase | S3335 | | SPARK depletion timecourse phosphoproteome |
TGGT1_295710 | HECT-domain (ubiquitin-transferase) domain-containing protein | HECT E3 | S2166, S4313 | | SPARK depletion timecourse phosphoproteome, PKA R depletion timecourse phosphoproteome |
TGGT1_216130 | putative ubiquitin conjugating enzyme E2 | putative E2 enzyme | S193 | | SPARK depletion timecourse phosphoproteome, PKA R depletion timecourse phosphoproteome |
TGGT1_293670 | transcription elongation factor A TFIIS | TFIIS | S356 | | SPARK depletion timecourse phosphoproteome |
TGGT1_226810 | histone lysine methyltransferase SET1 | SET1 | S1780 and S1781 | | PKA C3 and SPARK depletion timecourse phosphoproteome |
TGGT1_218070 | hypothetical protein | NOC3p | S1343 | | PKA C3 and SPARK depletion timecourse phosphoproteome |
TGGT1_280800 | SWI2/SNF2 SRCAP/Ino80 | TgSRCAP | S635 and S638 | Sullivan et al., 2003 | SPARK depletion timecourse phosphoproteome |
TGGT1_306660 | RNA pseudouridine synthase superfamily protein | PUS1 | S506 | Anderson et al., 2009 | SPARK depletion timecourse phosphoproteome |
TGGT1_312370 | RNA pseudouridine synthase superfamily protein | PUS protein | S951 | | SPARK depletion timecourse phosphoproteome |
TGGT1_231970 | pre-mRNA processing splicing factor PRP8 | PRP8 | T820 | | SPARK depletion timecourse phosphoproteome |
TGGT1_310820 | putative SLU7 splicing factor | SLU7 | S[516-519] | | SPARK depletion timecourse phosphoproteome |
TGGT1_267600 | FHA domain-containing protein | a FHA protein | S406 and S413 | | SPARK depletion timecourse phosphoproteome |
TGGT1_216670 | FUSE-binding protein 2/KH type splicing regulatory protein | KH protein | S8 | | PKA R, PKA C3, and SPARK depletion phosphoproteome |
TGGT1_241170 | hypothetical protein | KH protein | S362, S368, and S665 | | SPARK depletion timecourse phosphoproteome |
TGGT1_235930 | domain K- type RNA binding proteins family protein | KH protein | S58 and S59 | Farhat et al., 2021 | SPARK depletion timecourse phosphoproteome |
TGGT1_227450 | hydrolase, NUDIX family protein | DCP2 homolog | T1982 and S1985 | | SPARK depletion timecourse phosphoproteome |
TGGT1_260600 | Pumilio-family RNA binding repeat-containing protein | PUF1 | S225 | Joyce et al., 2013; Liu et al., 2014 | SPARK depletion timecourse phosphoproteome |
TGGT1_246040 | MIF4G domain-containing protein | MIF4G domain protein | S341 and S383 | | SPARK depletion timecourse phosphoproteome |
TGGT1_249610 | hypothetical protein | CBP80 | S851 and S853 | Gissot et al., 2013 | PKA C3 and SPARK depletion timecourse phosphoproteome |
TGGT1_317720 | putative eukaryotic translation initiation factor 3 subunit 7 | eIF3 | S587 | | SPARK depletion timecourse phosphoproteome |
TGGT1_231480 | putative GCN1 | GCN1 | S1100 | | SPARK depletion timecourse phosphoproteome |
TGGT1_251630 | slc30a2 protein | TgZnT | S448 | Chasen et al., 2019 | PKA C3 and SPARK depletion timecourse phosphoproteome |
TGGT1_288540 | nucleoside transporter protein | nucleoside transporter | | | SPARK depletion timecourse phosphoproteome |
TGGT1_260310 | ATP-binding cassette transporter ABC.B1 | ABC transporter | | | SPARK depletion timecourse phosphoproteome |
TGGT1_318710 | ATP-binding cassette sub-family F member 1 | ABC transporter | | | SPARK depletion timecourse phosphoproteome |
TGGT1_280660 | HECT-domain (ubiquitin-transferase) domain-containing protein | putative HECT-domain E3 ubiquitin ligase | S5275 and S5279 | | SPARK TurboID, SPARK depletion timecourse phosphoproteome |
TGGT1_286470 | AGC kinase | PKA C3 | | Sugi et al., 2016 | SPARK TurboID |
TGGT1_218240 | hypothetical protein | IMC25 | S1231 | Wang et al., 2016 | PKA R and SPARK depletion phosphoproteome |
TGGT1_220900 | hypothetical protein | AC13 | S101, S220, S659 | Back et al., 2023 | PKA R, PKG, PKA C3, and SPARK depletion phosphoproteome |
TGGT1_225690 | hypothetical protein | CIP1 | S850 and S851 | Long et al., 2017 | PKA R and SPARK depletion phosphoproteome |
TGGT1_257300 | hypothetical protein | CIP2 | S26 | Long et al., 2017 | PKA R and SPARK depletion phosphoproteome |
TGGT1_308860 | hypothetical protein | AC3 | S216 | Chen et al., 2015 | PKA R and SPARK depletion phosphoproteome |
TGGT1_315150 | putative eukaryotic initiation factor-4E | eIF4E | S1231 | | PKA R and SPARK depletion phosphoproteome |
TGGT1_235930 | domain K- type RNA binding proteins family protein | KH protein | S58 and S59 | Farhat et al., 2021 | PKA R and SPARK depletion phosphoproteome |
TGGT1_251640 | ubiquitin-conjugating enzyme subfamily protein | E2 protein | S23 | | PKA R and SPARK depletion phosphoproteome |
TGGT1_253700 | transporter, major facilitator family protein | MFS transporter | S144, S1287, S1288 | | PKG and SPARK depletion phosphoproteome |
TGGT1_312100 | plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 | TgA1 | S444 and S445 | | PKG and SPARK depletion phosphoproteome |
TGGT1_314780 | myosin G | MyoG | T1300 | Frénal et al., 2017 | PKG and SPARK depletion phosphoproteome |
TGGT1_295360 | hypothetical protein | IMC18 | S159, S161, and S165 | Chen et al., 2015 | PKG and SPARK depletion phosphoproteome |
TGGT1_239400 | hypothetical protein | IMC28 | S1081 and S1082 | Chen et al., 2017 | PKG and SPARK depletion phosphoproteome |
TGGT1_225560 | hypothetical protein | IMC41 | S440 | Back et al., 2023 | PKG and SPARK depletion phosphoproteome |
TGGT1_313480 | hypothetical protein | AAP3 | S178 | Engelberg et al., 2020 | PKG and SPARK depletion phosphoproteome |
TGGT1_235380 | hypothetical protein | AC5/TLAP3 | S463 | Chen et al., 2015; Liu et al., 2013 | PKG and SPARK depletion phosphoproteome |
TGGT1_263520 | microtubule associated protein SPM1 | SPM1 | S54 and S57 | Tran et al., 2012 | PKG and SPARK depletion phosphoproteome |
TGGT1_211710 | TB2/DP1, HVA22 family protein | TB2/DP1, HVA22 family proteins | S155 and S177 | | PKG and SPARK depletion phosphoproteome |
TGGT1_257040 | TB2/DP1, HVA22 family protein | TB2/DP1, HVA22 family proteins | S32 | | PKG and SPARK depletion phosphoproteome |
TGGT1_229490 | tetratricopeptide repeat-containing protein | TPR protein TGGT1_229490 | S456, S570 and S575 | | PKG and SPARK depletion phosphoproteome |
TGGT1_246600 | ABC1 family protein | ER ABC transporter | T1278 | | PKG and SPARK depletion phosphoproteome |
TGGT1_232190 | Sec7 domain-containing protein | Sec7 protein | S180 | | PKG and SPARK depletion phosphoproteome |
TGGT1_224150 | hypothetical protein | TgCOG6 | T533 and T673 | Marsilia et al., 2023 | PKG and SPARK depletion phosphoproteome |
TGGT1_203910 | TBC domain-containing protein | TgTBC10 | T254 and S256 | Quan et al., 2023 | PKG and SPARK depletion phosphoproteome |
TGGT1_250870 | DHHC zinc finger domain-containing protein | TgDHHC1 | S345 and S348 | Frénal et al., 2013 | PKG and SPARK depletion phosphoproteome |
TGGT1_212820 | ubiquitin family protein | ubiquitin family protein with a C-terminal extension | S368 | | PKG and SPARK depletion phosphoproteome |
TGGT1_290970 | 8-amino-7-oxononanoate synthase | TgSPT2 | | Nyonda et al., 2022 | PKA C3 depletion transcriptome |
TGGT1_259020 | bradyzoite antigen BAG1 | BAG1 | | Behnke et al., 2008 | PKA C3 depletion transcriptome |
TGGT1_253440 | cell-cycle-associated protein kinase SRPK, putative | SRPK | | Talevich et al., 2011 | PKA C3 IP-MS |
TGGT1_268960 | putative 5'-AMP-activated protein kinase subunit beta-1 family protein | AMPK subunit beta | | Yang et al., 2022 | PKA C3 IP-MS |
TGGT1_209985 | cAMP-dependent protein kinase | secreted cAMP-dependent protein kinases | | | PKA C3 depletion proteome |
TGGT1_356400 | cAMP-dependent protein kinase | secreted cAMP-dependent protein kinases | | | PKA C3 depletion proteome |
TGGT1_277790 | hypothetical protein | DEP domain protein | S586-600 | | PKA C3 depletion phosphoproteome |
TGGT1_318150 | transporter, major facilitator family protein | TgApiAT3-1 | S54 | | PKA C3 and SPARK depletion phosphoproteomes |
TGGT1_259260 | membrane protein FtsH1 | FtsH1 | S553 | | PKA C3 depletion phosphoproteome |
TGGT1_227280 | dense granule protein GRA3 | GRA3 | S120, T145, S197 | | PKA C3 depletion phosphoproteome |
TGGT1_312420 | hypothetical protein | GRA38 | S457 | Nadipuram et al., 2016 | PKA C3 depletion phosphoproteome |
TGGT1_204340 | hypothetical protein | CST8 | T601 | Tu et al., 2020 | PKA C3 depletion phosphoproteome |
TGGT1_230180 | hypothetical protein | GRA24 | T144 | Braun et al., 2013 | PKA C3 depletion phosphoproteome |
TGGT1_269180 | MIF4G domain-containing protein | eIF4G1 | S1312 | Holmes et al., 2023 | PKA C3 depletion phosphoproteome |
TGGT1_218300 | zinc finger (CCCH type) motif-containing protein | zinc finger protein | S663 | | PKA C3 depletion phosphoproteome |
TGGT1_209500 | hypothetical protein | DNA repair protein | S619 | | PKA C3 depletion phosphoproteome |
TGGT1_310450 | putative myosin heavy chain | IAP2 | T1269 | | PKA C3 depletion phosphoproteome |
TGGT1_273050 | hypothetical protein | BCC8 | | Liang et al., 2021 | PKA C3 depletion phosphoproteome |
TGGT1_287240 | hypothetical protein | condensin 2 | | | PKA C3 depletion phosphoproteome |
TGGT1_278660 | putative P-type ATPase4 | ATP4 | S83 and T166 | | PKA C3 depletion phosphoproteome |
TGGT1_233130 | nucleoside transporter protein | nucleoside transporter | S6 | | PKA C3 depletion phosphoproteome |
TGGT1_292020 | GCC2 and GCC3 domain-containing protein | CRMPb | S7300, S7303, S7363, and S7365 | Singer et al., 2023; Sparvoli et al., 2022 | PKA C3 depletion phosphoproteome |
TGGT1_221180 | hypothetical protein | microneme protein | S788 | | PKA C3 depletion phosphoproteome |
TGGT1_304490 | hypothetical protein | microneme protein | S10 | | PKA C3 depletion phosphoproteome |
TGGT1_309590 | rhoptry protein ROP1 | ROP1 | T248 | | PKA C3 depletion phosphoproteome |
TGGT1_211290 | rhoptry protein ROP15 | ROP13 | S312 | | PKA C3 depletion phosphoproteome |
TGGT1_258580 | rhoptry protein ROP17 | ROP17 | T51 | | PKA C3 depletion phosphoproteome |
TGGT1_291960 | rhoptry kinase family protein ROP40 (incomplete catalytic triad) | ROP40 | S98 | | PKA C3 depletion phosphoproteome |
TGGT1_308810 | rhoptry neck protein RON9 | RON9 | S190, S239, S327, and S375 | | PKA C3 depletion phosphoproteome |
TGGT1_310780 | dense granule protein GRA4 | GRA4 | S248 | | PKA C3 depletion phosphoproteome |
TGGT1_275440 | dense granule protein GRA6 | GRA6 | S133 and S134 | | PKA C3 depletion phosphoproteome |
TGGT1_203310 | dense granule protein GRA7 | GRA7 | S62, S72, S77, S135, S153 | | PKA C3 depletion phosphoproteome |
TGGT1_254720 | dense granule protein GRA8 | GRA8 | S198, T202, T262 | | PKA C3 depletion phosphoproteome |
TGGT1_220240 | hypothetical protein | GRA31 | S420 | Nadipuram et al., 2020; Young et al., 2020 | PKA C3 depletion phosphoproteome |
TGGT1_217680 | hypothetical protein | GRA57 | S806 | Krishnamurthy et al., 2023; Nadipuram et al., 2020; Young et al., 2020 | PKA C3 depletion phosphoproteome |
TGGT1_215360 | hypothetical protein | GRA62 | S319 | Cygan et al., 2021 | PKA C3 depletion phosphoproteome |
TGGT1_249990 | hypothetical protein | GRA70 | S436 | Krishnamurthy et al., 2023; Lockyer et al., 2023 | PKA C3 depletion phosphoproteome |
TGGT1_289540 | hypothetical protein | SFP1 | S897 | Young et al., 2020 | PKA C3 depletion phosphoproteome |
TGGT1_251740 | AP2 domain transcription factor AP2XII-9 | AP2XII-9 | S1697 | | PKA C3 depletion phosphoproteome |
TGGT1_273870 | SWI2/SNF2 ISWI-like (AT hook) | ISWI protein | T765 | | PKA C3 depletion phosphoproteome |
TGGT1_260240 | hypothetical protein | CAF1 | S272 | | PKA C3 depletion phosphoproteome |
TGGT1_253750 | PLU-1 family protein | PLU-1 | S3874 and S3877 | Wang et al., 2014 | PKA C3 depletion phosphoproteome |
TGGT1_300330 | hypothetical protein | GCFC | S27 | | PKA C3 depletion phosphoproteome |
TGGT1_223880 | zinc finger, C3HC4 type (RING finger) domain-containing protein | zinc finger protein | S3701 | | PKA C3 depletion phosphoproteome |
TGGT1_288380 | heat shock protein HSP90 | HSP90 | S600 | | PKA C3 depletion phosphoproteome |
TGGT1_321520 | hypothetical protein | p23 | S109 | | PKA C3 depletion phosphoproteome |
TGGT1_225450 | hypothetical protein | CSN3 | S509 and S517 | | PKA C3 depletion phosphoproteome |
TGGT1_242890 | hypothetical protein | PSME4 | S3127 | | PKA C3 depletion phosphoproteome |
TGGT1_218960 | AP2 domain transcription factor AP2XII-1 | AP2XII-1 | T1697, S1702, T1667, T1703 | Antunes et al., 2024 | PKA C3 depletion phosphoproteome |
TGGT1_262150 | kelch repeat and K+channel tetramerisation domain containing protein | Kelch13 | S139 | Harding et al., 2020; Koreny et al., 2023; Wan et al., 2023 | PKA C3 depletion phosphoproteome |
TGGT1_254940 | MIF4G domain-containing protein | eIF4G2 | S985 and S989 | Holmes et al., 2023 | PKA C3 and SPARK depletion phosphoproteomes |
TGGT1_320020 | transporter, major facilitator family protein | TgApiAT2 | S316 and T318 | | PKA C3 and SPARK depletion phosphoproteomes |
TGGT1_233000 | KOW motif domain-containing protein | Spt5 | S1011 and S1014 | | PKA C3 and SPARK depletion phosphoproteomes |
TGGT1_279320 | hypothetical protein | nucleotidyltransferase | S4010 | | PKA C3 and SPARK depletion phosphoproteomes |
TGGT1_313180 | putative cell-cycle-associated protein kinase PRP4 | PRP4 | S316 | Swale et al., 2022 | |
TGGT1_214140 | hypothetical protein | associates with AP2IX4/MORC complex | S205 and S212 | | |
TGGT1_309250 | hypothetical protein | associates with GCN5b complex | PMID: 31381949 and 24391497 | | |