Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood

    Carlos Ruiz-Arenas et al.
    A catalogue of associations between DNA methylation and gene expression in children will improve the interpretation of Epigenome-Wide Association Studies.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Environmentally sensitive hotspots in the methylome of the early human embryo

    Matt J Silver et al.
    259 CpGs associated with season of conception in rural Gambians constitute a valuable resource for investigating epigenetic mechanisms linking early exposures to lifelong health and disease.
    1. Epidemiology and Global Health
    2. Medicine

    External validation of a mobile clinical decision support system for diarrhea etiology prediction in children: A multicenter study in Bangladesh and Mali

    Stephanie Chow Garbern et al.
    A smartphone app incorporating clinical prediction models using patient-specific and location-specific data sources in a modular approach could predict viral-only etiology of diarrhea in children under five in Bangladesh and Mali.
    1. Epidemiology and Global Health
    2. Medicine

    Investigating phenotypes of pulmonary COVID-19 recovery: A longitudinal observational prospective multicenter trial

    Thomas Sonnweber et al.
    Protracted systemic and microvascular inflammation, as well as high anti-SARS-CoV-2 antibody levels, is associated with a high risk of persistent structural and functional lung deficits 6 months after COVID-19.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Epigenetic scores for the circulating proteome as tools for disease prediction

    Danni A Gadd et al.
    Epigenetic scores for blood protein levels identify those at risk of multiple age-related morbidities, up to 14 years prior to onset.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Biomarkers: Getting closer to the clinic

    Toshiko Tanaka, Luigi Ferrucci
    Associations between plasma protein levels and DNA methylation patterns can be used to predict the onset of age-related chronic disease.
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    1. Epidemiology and Global Health

    Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

    Ellen A Kearney et al.
    A systematic review with multilevel modelling quantified the positive association between human antibodies to Anopheles salivary proteins with Anopheles-human biting rate and epidemiological measures of malaria transmission, highlighting their potential as a tool to measure vector exposure and malaria transmission.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    DunedinPACE, a DNA methylation biomarker of the pace of aging

    Daniel W Belsky et al.
    DunedinPACE is a novel DNA methylation biomarker of the pace of biological aging for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by environmental modification.
    1. Epidemiology and Global Health

    Adverse childhood experiences and resilience among adult women: A population-based study

    Hilda Björk Daníelsdóttir et al.
    Cumulative exposure to adverse childhood experiences is associated with lower adult resilience among women in a dose-dependent manner, independent of adult socioeconomic factors and social support, indicating that adult female resilience is consolidated in early life.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Primate malarias as a model for cross-species parasite transmission

    Marina Voinson et al.
    Ecological and evolutionary perspectives are critical to understand, predict, prevent, and treat malaria parasites that may spread to humans from our close primate relatives.