Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Integrating genomic and epidemiologic data to accelerate progress toward schistosomiasis elimination

    Andrea J Lund, Kristen J Wade ... Elizabeth J Carlton
    Genomic approaches can be integrated with epidemiological and ecological studies to provide high-resolution answers to open questions about schistosomiasis transmission dynamics, offering a level of precision that is actionable, such that schistosomiasis-control programming can be tailored to regional contexts.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans

    Susanna Lemmelä, Eleanor M Wigmore ... Athena Matakidou
    Elevated growth differentiation factor-15 (GDF15) levels do not appear to be a causal factor in body mass index (BMI) in humans but higher BMI does cause increases in GDF15.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    The unmitigated profile of COVID-19 infectiousness

    Ron Sender, Yinon Bar-On ... Ron Milo
    In the absence of COVID-19 mitigation measures, SARS-CoV-2 remains infectious for longer than previously estimated.
    1. Epidemiology and Global Health

    Global variation in force-of-infection trends for human Taenia solium taeniasis/cysticercosis

    Matthew A Dixon, Peter Winskill ... María-Gloria Basáñez
    Marked geographical heterogeneity in global Taenia solium transmission rates indicate the need for setting-specific intervention strategies to achieve the WHO NTD 2021-2030 roadmap milestones for T. solium.
    1. Epidemiology and Global Health

    Effects of side-effect risk framing strategies on COVID-19 vaccine intentions: a randomized controlled trial

    Nikkil Sudharsanan, Caterina Favaretti ... Alain Vandormael
    Small changes to the way COVID-19 vaccine side-effect rates are framed and communicated have meaningful impacts on individuals' vaccination intentions.
    1. Epidemiology and Global Health

    COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)

    Wan Yang, Jeffrey L Shaman
    Model-inference reconstructed SARS-CoV-2 transmission dynamics in South Africa during March 2020 to February 2022, and quantified the immune erosion potential and transmissibility of three major variants (Beta, Delta, and Omicron), highlighting their common characteristics and the need for more proactive preparedness.
    1. Epidemiology and Global Health

    Adiposity may confound the association between vitamin D and disease risk – a lifecourse Mendelian randomization study

    Tom G Richardson, Grace M Power, George Davey Smith
    Genetic analyses provide evidence that adiposity influences vitamin D levels at different timepoints over the lifecourse, suggesting that associations previously reported between vitamin D deficiency and disease by conventional epidemiological studies may have been prone to confounding.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Genomic epidemiology of the first two waves of SARS-CoV-2 in Canada

    Angela McLaughlin, Vincent Montoya ... Jeffrey B Joy
    Canadian COVID-19 travel restrictions imposed in March 2020 greatly reduced SARS-CoV-2 importations, but were insufficient to prevent new sublineages of similar transmissibility from being introduced and replacing early sublineages.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

    Fei Chen, Burcu F Darst ... Christopher A Haiman
    A previously developed multi-ancestry polygenic risk score is potentially an effective prostate cancer risk stratification tool across ancestry populations.
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