A new method enables engineered immune progenitor cells to replace microglia in mice and reveals how a genetic mutation can lead to inflammation in the brain.
Comprehensive mapping of wing sensory neurons in Drosophila reveals that some proprioceptors make direct connections onto flight steering motor neurons, enabling rapid feedback control during flight.
Stress activates a locus coeruleus–spinal dorsal horn noradrenergic circuit that drives mechanical pain hypersensitivity through Hes5-positive astrocytes.