For the first time, mouse models reveal the metabolic dependency of photoreceptors on glutamine catabolism in vivo and further demonstrate the flexibility of photoreceptors to utilize fuel sources beyond glucose.
Marius Seidenthal, Jasmina Redzovic ... Alexander Gottschalk
Caenorhabditis elegans FLWR-1/Flower is required for efficient synaptic vesicle recycling and does so through a functional and possibly direct physical interaction with the plasma membrane Ca2+ ATPase, MCA-3.
Philip Stavrides, Chris N Goulbourne ... Dun-Sheng Yang
ALP alterations in Q175 brains are late-onset, mild, existing at the later phases of the pathway, and stimulating autophagy at early disease progression enhances mHTT clearance to ameliorate HD pathology.
It is proposed that place cells are arranged in a hexagonal grid for large surfaces devoid of landmarks, which produces grid cell receptive fields as an artifact of memory retrieval.
Sarah Benkeder, Son-Michel Dinh ... Jean-Christophe Comte
MorphoCellSorter is a versatile, user-friendly tool that automates microglial morphology ranking, enabling standardized, reproducible analysis across diverse models, imaging techniques, and conditions using principal component analysis and Andrews plots.
As a group, inattentionally blind participants can successfully report the location, color, and shape of stimuli they deny noticing, and exhibit a systematic bias to report not noticing.
Daniela Piña Novo, Mang Gao ... Gordon MG Shepherd
'Phototactile' hand stimulation rapidly activates first the somatosensory then the motor cortex, broadly consistent with constraints suggested by the previously described circuit architecture of this transcortical loop.
