Viral-mediated Oct4 overexpression induces direct conversion of wildtype mammalian Müller glia to bipolar neurons, and this process is synergistically enhanced by loss of Notch signaling.
Rare individuals treated for congenital cataracts demonstrated shifts in the visual cortex’s excitatory/inhibitory balance even decades post-surgery, reflected by alterations in the neurotransmitter concentration ratio and aperiodic electroencephalogram activity.
Lili Karashchuk, Jing Shuang Li ... Bingni W Brunton
A model that simulates realistic fly walking uses an anatomically-inspired layered architecture to achieve robust walking, quantifying the tolerance of this circuit to sensorimotor delays.
Matthew Rosenblatt, Saloni Mehta ... Dustin Scheinost
Self-citation rates differed by geographic region, seniority, gender, and field, which may ultimately affect the perceived influence of authors in these subgroups in neuroscience literature.
Noëmie Mermet-Joret, Andrea Moreno ... Sadegh Nabavi
An optogenetic system capable of precise, high-frequency neuronal excitation using red pulsed light and rapid, millisecond inhibition using blue light.