Intrinsic cell cycle progression governs developmental time in neural stem cells by regulating temporal gene transitions that generate neural diversity.
Eric R Wengert, Sophie R Liebergall ... Ethan M Goldberg
Brain slice electrophysiology, immunohistochemistry, and in vivo two-photon calcium imaging identify circuit dysfunction and epilepsy mechanism in a Kcnc1-A421V/+ mouse model of developmental and epileptic encephalopathy.
Counterconditioning improved safety memory retrieval over regular extinction, showing a shift away from vmPFC towards nucleus accumbens, and may thereby be a promising new treatment option.
Francesca S Wong, Simon Killcross ... Nathan M Holmes
The basolateral amygdala complex and perirhinal cortex function like the focal and peripheral states of attention described by classic associative learning theories.
Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.
Adam A Atanas, Alicia Kun-Yang Lu ... Steven W Flavell
New machine vision tools are used to align densely packed cells recorded from live, deforming tissues and automatically annotate the identities of the recorded cell types.