Browse our latest Neuroscience articles

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    1. Genetics and Genomics
    2. Neuroscience

    Rapid and inducible mislocalization of endogenous TDP43 in a novel human model of amyotrophic lateral sclerosis

    Johanna Ganssauge, Sophie Hawkins ... Akshay Bhinge
    A novel human iPSC-derived model induces mislocalization of endogenous TDP-43 without mutations or stress, recapitulating key ALS features including deficits in neuronal loss and morphology, splicing errors, and microRNA dysregulation.
    1. Neuroscience

    The NIH BRAIN Initiative’s impacts in systems and computational neuroscience and team-scale research 2014–2023

    Farah Bader, Clayton Bingham ... James Gnadt
    The BRAIN Circuits Program of the NIH BRAIN Initiative has impacted how fundamental discovery in integrative systems neuroscience is investigated, commensurate with the complexity to address neurobehavioral and neurological dysfunctions.
    1. Neuroscience

    Social rank-order stability of mice revealed by a novel food competition paradigm in combination with available space competition paradigms

    Meiqiu Liu, Yue Chen, Rongqing Chen
    Social status of mice in an established colony is stably expressed in several types of competition paradigms, including food and space competitions.
    1. Developmental Biology
    2. Neuroscience

    Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development

    Saman Hussain, Katherine Pinter ... Katie S Kindt
    Formation of specialized ribbon synapses in sensory hair cells involves dynamic precursor movement, microtubule-guided transport, and precursor fusion, culminating in synapse assembly essential for hearing and balance.
    1. Neuroscience

    Sexual failure decreases sweet taste perception in male Drosophila via dopaminergic signaling

    Gaohang Wang, Wei Qi ... Liming Wang
    Failure in sexual behaviors suppresses sweet taste perception of male fruit flies, by dampening dopaminergic signaling between mating-related neural circuits and peripheral gustatory pathways.
    1. Developmental Biology
    2. Neuroscience

    Ribbon Synapses: Taking the tube to the basal pole of hair cells

    Satish R Ghimire, Thomas M Coate
    A stable microtubule network and kinesin motors facilitate the formation of presynaptic ribbons in sensory hair cells in the zebrafish lateral line.
    Version of Record
    Insight
    1. Neuroscience

    Identification of novel human microcephaly-linked protein Mtss2 that mediates cortical progenitor cell division and corticogenesis through Nedd9-RhoA

    Aurelie Carabalona, Henna Kallo ... Claudio Rivera
    ABBA ensures proper cortical development by regulating radial glial division through RhoA activity at the cleavage furrow, and its mutation results in developmental abnormalities linked to microcephaly.
    1. Neuroscience
    2. Evolutionary Biology

    Investments in photoreceptors compete with investments in optics to determine eye design

    Francisco JH Heras, Simon B Laughlin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Synaptic Encoding of Time in Working Memory

    Gianluigi Mongillo, Misha Tsodyks
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Increased listening effort and cochlear neural degeneration underlie speech-in-noise deficits in normal-hearing middle-aged adults

    Maggie E Zink, Leslie Zhen ... Aravindakshan Parthasarathy
    Cochlear neural degeneration in middle-aged adults with normal-hearing thresholds is associated with increased listening effort and behavioral deficits in challenging acoustic environments.