Browse our latest Neuroscience articles

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    1. Neuroscience

    Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation)

    James B Isbister, András Ecker ... Michael W Reimann
    A general and open multiscale cortical model is presented which can be used by the community to study neural coding, spike sorting, plasticity, optogenetic and extracellular stimulation, local field potential, and electroencephalography.
    1. Neuroscience

    Modeling and simulation of neocortical micro- and mesocircuitry (Part I, anatomy)

    Michael W Reimann, Sirio Bolaños-Puchet ... Srikanth Ramaswamy
    A morphologically detailed model of brain region anatomy serves as the foundation for biophysically detailed simulations and provides insights into local and inter-regional connectivity.
    1. Computational and Systems Biology
    2. Neuroscience

    Predicting human decision-making across task conditions via individuality transfer

    Hiroshi Higashi
    Encoding individual behavioral traits into a low-dimensional latent representation enables the accurate prediction of decision-making patterns across distinct task conditions.
    1. Neuroscience

    Aging: Linking neuron-glia interactions and longevity

    Michael Pokrass, Nan Hao
    Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.
    Version of Record
    Insight
    1. Neuroscience

    Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning

    Glingna Wang, Nan Zhou ... Jai Y Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    Biologically informed cortical models predict optogenetic perturbations

    Christos Sourmpis, Carl CH Petersen ... Guillaume Bellec
    Multi area RNN models fitted to in-vivo cortical activity predict behavioral changes induced by optogenetic perturbations, if biologically informed connectivity constraints on the optogenetically targeted inhibitory neurons are applied.
    1. Neuroscience

    Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

    Abhilasha Joshi, Alison E Comrie ... Loren M Frank
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Computational and Systems Biology
    2. Neuroscience

    A dynamic scale-mixture model of motion in natural scenes

    Jared M Salisbury, Stephanie E Palmer
    A simple statistical model captures the essential features of object motion in a large database of natural scenes, helping to shed light on the challenges posed to sensory and motor systems.
    1. Immunology and Inflammation
    2. Neuroscience

    Trained immunity in acute and chronic neurological diseases

    Sijia Zhang, Arthur Liesz
    Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation across neurological diseases, offering new insights into disease mechanisms and potential therapeutic strategies.
    1. Neuroscience

    Neural Traces of Forgotten Memories Persist in Humans and are Behaviorally Relevant

    Tom Willems, Konstantinos Zervas ... Katharina Henke
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete