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    1. Neuroscience

    Dissociable roles of reward prediction error in the contrasting mood dynamics of depression and anxiety

    Zhihao Wang, Ting Wang ... Pengfei Xu
    Depression-specific symptoms blunt mood responses to unexpected outcomes, whereas anxiety-specific symptoms amplify them in non-clinical participants, with depression-related blunting also replicated in patients with affective disorders.
    1. Neuroscience

    PKD2L1 channels segregated to the apical compartment are the dual-mode pH sensor in cerebrospinal fluid-contacting neurons

    Magdalena Vitar, Daniel Prieto ... Federico F Trigo
    Apical PKD2L1 channels generate phasic and sustained currents that together make spinal cerebrospinal fluid-contacting neurons exquisite pH sensors.
    1. Neuroscience

    Invariant synaptic density across species

    André Ferreira Castro, Albert Cardona
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    When word order matters: human brains represent sentence meaning differently from large language models

    James Fodor, Carsten Murawski, Shinsuke Suzuki
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

    Daniel Beaudet, Christopher L Berger, Adam G Hendricks
    Single-molecule motility assays and live-cell imaging in neurons reveal that tau hyperphosphorylation disrupts the formation of cooperative tau envelopes along microtubules and lysosomal transport.
    1. Neuroscience

    Selective lifelong suppression of an odor processing channel in response to critical period experience

    Hans C Leier, Julius Jonaitis ... Andrew M Dacks
    Utilizing the olfactory system of Drosophila, a critical period paradigm has provided new insight into the selectivity and longevity of the impact of early life experiences on sensory system circuitry.
    1. Medicine
    2. Neuroscience

    Reverse engineering of motor unit discharge in multiple sclerosis reveals heterogeneity of voluntary motor commands

    Laura M McPherson, Keith R Lohse ... Anne H Cross
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Medicine
    2. Neuroscience

    Synthetic torpor in the rat protects the heart from ischaemia-reperfusion injury

    Megan Elley, Ludovico Taddei ... Michael Ambler
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Opening the black box toward a modular approach to spike sorting

    Samuel Garcia, Chris Halcrow ... Pierre Yger
    Modularized spike sorting pipelines can identify performance bottlenecks, lower contribution barriers, and enable the development of highly accurate algorithms to turn extracellular recordings into spikes.
    1. Neuroscience

    Retinal curl as a functional signal for heading estimation beyond the focus of expansion

    Kontessa I Zorpala, Joan López-Moliner
    The rotational retinal flow generated by natural gaze stabilization is not merely visual noise to be subtracted but actively shapes human heading perception.
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