The brain computes rapidly and reliably using brief electrical impulses and likely exploits internal memory in nerve cells to achieve this more efficiently than existing computing hardware and neural networks.
Flexible evidence accumulation in dynamic environments relies on multiple mechanisms, including context-dependent modulations of sensory adaptation and pupil-linked arousal.
Double-knockout of PKMζ and the other atypical PKC, PKCι/λ, reveals that, without PKMζ for maintenance, PKCι/λ becomes persistently active to sustain hippocampal late-LTP and long-term memory.
