Browse our latest Stem Cells and Regenerative Medicine articles

Single-cell transcriptomics analysis identifies the dynamic activity of transcription factors at the onset of hematopoeitic stem and progenitor cells formation during embryonic development.

Estrogen is a systemic factor that promotes hematopoietic regeneration by activating the unfolded protein responses.

The CtBP protein stabilizes cell fates in regenerating tissue.

Müller glia cells in the medaka (Oryzias latipes) retina act as lineage restricted progenitors which only regenerate photoreceptors but can be activated to perform as potent stem cells using Sox2.

Wound-specific notochord sheath cell subpopulations associate with notochord repair and adult vertebrae formation.

rDNA copy number is shown to dynamically change during aging and through generations, and is actively maintained in male germline of Drosophila.

During reprogramming of human fibroblasts to naïve iPSCs there is transient reactivation of transcripts with the characteristics of 8-cell-stage-embryos.

Micropatterned differentiation of mouse pluripotent stem cells gives rise to regionally distinct cell types arising in embryos at gastrulation.

Analyses of genetically engineered mouse models reveal the androgen receptor-independent properties of a luminal stem/progenitor cell in the prostate epithelium, and its ability to serve as a cell of origin for castration-resistant prostate cancer.

Genetic manipulations show that endogenous transcription factors of the SoxB1 class act redundantly to maintain primed pluripotency and reveal differential effects on transitions between pluripotent and differentiation states.