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    1. Neuroscience

    Spontaneous fluctuations in global connectivity reflect transitions between states of high and low prediction error

    Paul C Bogdan, Shenyang Huang ... Roberto Cabeza
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution

    Alastair J Tulloch, Ryan N Delgado ... Constance L Cepko
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Dynamics of mesoscale brain network during visual discrimination learning revealed by chronic, large-scale single-unit recording

    Tian-Yi Wang, Chengcong Feng ... Zhengtuo Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

    Sen-Lin Lai, Chris Q Doe
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Impacts of DNA Methylation on H2A.Z Deposition and Nucleosome Stability

    Rochelle M Shih, Yasuhiro Arimura ... Hironori Funabiki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation is associated with the subsequent reduction in the viral reservoir

    Pien Margien van Paassen, Alexander O Pasternak ... Godelieve J de Bree
    In individuals who started antiretroviral therapy during acute HIV infection, the proliferative capacity of HIV-specific CD8+ T-cells at 24 weeks of therapy predicted the subsequent reduction in the viral reservoir.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV

    Céline Fombellida-Lopez, Aurelija Valaitienė ... Gilles Darcis
    In a randomized trial, ART intensification by doubling the dolutegravir dosage in people with HIV stably suppressed on dolutegravir-based ART reduced levels of four HIV reservoir markers in peripheral blood.
    1. Cell Biology

    The IBEX knowledge-base a community resource enabling adoption and development of immunofluorescence imaging methods

    Ziv Yaniv, Ifeanyichukwu U Anidi ... Andrea J Radtke
    A dynamic, community-driven knowledge repository reduces research costs and accelerates scientific discovery by sharing validated reagent data, negative results, and protocols while rewarding contributors through formal authorship recognition.
    1. Cancer Biology
    2. Physics of Living Systems

    Robust assessment of asymmetric division in colon cancer cells

    Domenico Caudo, Chiara Giannattasio ... Mattia Miotto
    Combining statistical modeling with flow cytometry enables reliable, high-throughput quantification of division asymmetry in live cells, revealing how partitioning noise may shape tumor cell heterogeneity.
    1. Computational and Systems Biology
    2. Neuroscience

    Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum

    Aske Ejdrup, Jakob Kisbye Dreyer ... Ulrik Gether
    A computational model of the striatal dopamine system predicts transporter expression and organisation as key determinants of regional striatal dopamine dynamics and distinct signal decoding by D1 and D2 receptors.
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