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    1. Neuroscience

    Language comprehension functionally modulates first-order relay thalamic nuclei

    Liu Mengxing, Shiya Wang ... Pedro M Paz-Alonso
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced mechanical pain hypersensitivity

    Riku Kawanabe-Kobayashi, Sawako Uchiyama ... Makoto Tsuda
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Profiling presynaptic scaffolds using split-GFP reconstitution reveals cell-type-specific spatial configurations in the fly brain

    Hongyang Wu, Yoh Maekawa ... Hiromu Tanimoto
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Sleep-Wake Transitions Are Impaired in the AppNL-G-F Mouse Model of Early Onset Alzheimer’s Disease

    Ryan K Tisdale, Yu Sun ... Thomas S Kilduff
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Unravelling the neurocognitive mechanisms underlying counterconditioning in humans

    Lisa Wirz, Maxime C Houtekamer ... Erno Hermans
    Counterconditioning improved safety memory retrieval over regular extinction, showing a shift away from vmPFC towards nucleus accumbens, and may thereby be a promising new treatment option.
    1. Genetics and Genomics
    2. Neuroscience

    Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy

    Eric R Wengert, Sophie R Liebergall ... Ethan M Goldberg
    Brain slice electrophysiology, immunohistochemistry, and in vivo two-photon calcium imaging identify circuit dysfunction and epilepsy mechanism in a Kcnc1-A421V/+ mouse model of developmental and epileptic encephalopathy.
    1. Developmental Biology
    2. Neuroscience

    Cell cycle-dependent cues regulate temporal patterning of the Drosophila central brain neural stem cells

    Gonzalo N Morales Chaya, Mubarak Hussain Syed
    Intrinsic cell cycle progression governs developmental time in neural stem cells by regulating temporal gene transitions that generate neural diversity.
    1. Cell Biology
    2. Immunology and Inflammation

    Male-biased Cyp17a2 orchestrates antiviral sexual dimorphism in fish via STING stabilization and viral protein degradation

    Long-Feng Lu, Bao-jie Cui ... Shun Li
    Cyp17a2 enhances antiviral responses in male zebrafish by stabilizing STING through TRIM11-mediated K33-linked polyubiquitination, boosting IFN production.
    1. Neuroscience

    The basolateral amygdala complex and perirhinal cortex represent focal and peripheral states of information processing in rats

    Francesca S Wong, Simon Killcross ... Nathan M Holmes
    The basolateral amygdala complex and perirhinal cortex function like the focal and peripheral states of attention described by classic associative learning theories.
    1. Computational and Systems Biology

    Ribosome demand links transcriptional bursts to protein expression noise

    Sampriti Pal, Upasana Ray, Riddhiman Dhar
    Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.
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