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    1. Cancer Biology

    Nerve Injury-Induced Protein 2 preserves lysosomal membrane integrity to suppress ferroptosis

    Jin Zhang, Miranda Bustamante ... Xinbin Chen
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Genetics and Genomics

    Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

    Kuei Ching Hsiung, Hannah Chapman ... David Gems
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Dynamic modulation of social gaze by sex and familiarity in marmoset dyads

    Feng Xing, Alec G Sheffield ... Anirvan S Nandy
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Neuroscience

    Endogenous Precision of the Number Sense

    Arthur Prat-Carrabin, Michael Woodford
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration in human cancer cells

    Ravi Kumar, Simon Couly ... Ashish Lal
    Global proteomics and functional analyses reveal that p53-induced ZMAT3 suppresses mitochondrial respiration by inhibiting transcription of a hexokinase, uncovering a role for ZMAT3 in transcription.
    1. Developmental Biology
    2. Neuroscience

    The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

    Sen-Lin Lai, Chris Q Doe
    Fd4 is expressed in NB7-1 and new-born progeny where it activates terminal selector genes to produce lineage-specific neurons.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Dietary sulfur amino acid restriction elicits a cold-like transcriptional response in inguinal but not epididymal white adipose tissue of male mice

    Philip MM Ruppert, Aylin S Gueller ... Jan-Wilhelm Kornfeld
    Transcriptomic profiling on liver and adipose depots reveals tissue-specific and beige-fat–convergent responses to methionine restriction and cold, providing a high-quality resource to guide combinatorial lifestyle interventions for metabolic disease research.
    1. Neuroscience

    Identity and functions of monoaminergic neurons in the predatory nematode Pristionchus pacificus reveal nervous system conservation and divergence

    Curtis M Loer, Hyunsoo Yim ... Ray L Hong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Transcriptional responses to chronic oxidative stress require cholinergic activation of G-protein-coupled receptor signaling

    Kasturi Biswas, Caroline Moore ... Michael M Francis
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

    Tongtong Xu, Fujun Cao ... Chengjian Zhao
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
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