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Page 14 of 1,893
    1. Cell Biology

    Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism

    Fangqing Deng, Rong Yang ... Lianbing Zhang
    Periodic red-light irradiation promotes coupling between keratinocyte mitochondrial lipid metabolism and epigenetic remodeling, increasing acetyl-CoA availability and histone H3 lysine 9 acetylation to slow skin aging.
    1. Cell Biology

    Early recruitment of membrane-bound DNaseX to phagocytic cups in macrophages

    Arghajit Pyne, Vivek Pandey ... Xuefeng Wang
    Phagocytic cups of macrophages exhibit strong DNase activity during the early stage of phagocytosis, prior to cup closure.
    1. Genetics and Genomics

    A pleiotropic EPAS1 enhancer mediating Tibetan adaptation to hypoxia is active in adipocytes

    Alexis G Thornburg, Soo-Young Park ... Marcelo A Nóbrega
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Opposite and complementary roles of the two calcium thresholds for inducing LTP and LTD in models of striatal projection neurons

    Daniel Trpevski
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Heterogeneity and ontogeny of mouse thymic macrophages reveal a requirement for Csf1r-expressing myeloid cells during early T cell development

    Helen Wang, Vinothkumar Rajan ... Juan Carlos Zúñiga-Pflücker
    Two thymic macrophage subsets differ in developmental origin and specialize in apoptotic-cell clearance or immune signaling, linking the thymic myeloid niche to progression through the early β-selection-associated checkpoint.
    1. Evolutionary Biology

    Large scale loss-of-function mutations during chicken evolution and domestication

    Siwen Wu, Kun Wang ... Zhengchang Su
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Golgi CATCHR complexes function as organizing hubs for vesicle tethering and fusion

    Walter S Aragon-Ramirez, Amrita Khakurel ... Vladimir V Lupashin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    On the Polymorph-Selection Determinants of α-Synuclein Amyloid Fibrils Studied at Atomic Resolution

    Lukas Frey, David Rhyner ... Jason Greenwald
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Stem Cells and Regenerative Medicine

    GDNF regenerates the missing enteric nervous system of Hirschsprung mice via non-canonical signaling in diverse subtypes of tissue-resident progenitors

    Alassane Gary, Rodolphe Soret ... Nicolas Pilon
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Cis-regulation and natural selection in the evolution of human DNA methylation

    Zhenzhen Ma, Alexander L Starr ... Hunter B Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Solid
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