1. Neuroscience
Download icon

Visual field map clusters in human frontoparietal cortex

  1. Wayne E Mackey
  2. Jonathan Winawer
  3. Clayton E Curtis Is a corresponding author
  1. New York University, United States
Research Article
Cited
0
Views
338
Comments
0
Cite as: eLife 2017;6:e22974 doi: 10.7554/eLife.22974

Abstract

The visual neurosciences have made enormous progress in recent decades, in part because of the ability to drive visual areas by their sensory inputs, allowing researchers to reliably define visual areas across individuals and across species. Similar strategies for parcellating higher-order cortex have proven elusive. Here, using a novel experimental task and nonlinear population receptive field modeling we map and characterize the topographic organization of several regions in human frontoparietal cortex. We discover representations of both polar angle and eccentricity that are organized into clusters, similar to visual cortex, where multiple gradients of polar angle of the contralateral visual field share a confluent fovea. This is striking because neural activity in frontoparietal cortex is believed to reflect higher-order cognitive functions rather than external sensory processing. Perhaps the spatial topography in frontoparietal cortex parallels the retinotopic organization of sensory cortex to enable an efficient interface between perception and higher-order cognitive processes. Critically, these visual maps constitute well-defined anatomical units that future study of frontoparietal cortex can reliably target.

Article and author information

Author details

  1. Wayne E Mackey

    1. Center for Neural Science, New York University, New York, United States
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon 0000-0002-1577-9235
  2. Jonathan Winawer

    1. Center for Neural Science, New York University, New York, United States
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon 0000-0001-7475-5586
  3. Clayton E Curtis

    1. Center for Neural Science, New York University, New York, United States
    For correspondence
    1. clayton.curtis@nyu.edu
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon 0000-0003-0702-1499

Funding

National Institutes of Health (R01 EY016407)

  • Clayton E Curtis

National Institutes of Health (R00 EY022116)

  • Jonathan Winawer

National Science Foundation (Graduate Student Fellowship)

  • Wayne E Mackey

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.

Ethics

Human subjects: All subjects gave written informed consent before participating. All procedures were approved by the human subjects Institutional Review Board at New York University.

Reviewing Editor

  1. Jack L Gallant, Reviewing Editor, University of California, Berkeley, United States

Publication history

  1. Received: November 4, 2016
  2. Accepted: June 17, 2017
  3. Accepted Manuscript published: June 19, 2017 (version 1)

Copyright

© 2017, Mackey et al

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

Metrics

  • 338
    Page views
  • 85
    Downloads
  • 0
    Citations

Article citation count generated by polling the highest count across the following sources: PubMed Central, Scopus, Crossref.

Comments

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Download citations (links to download the citations from this article in formats compatible with various reference manager tools)

Open citations (links to open the citations from this article in various online reference manager services)