1. Neuroscience
Download icon

Connectomics: A network for swimming

  1. Yee Lian Chew
  2. William R Schafer  Is a corresponding author
  1. University of Cambridge, United Kingdom
Insight
Cite this article as: eLife 2017;6:e28780 doi: 10.7554/eLife.28780
1 figure

Figures

The ciliomotor circuitry of Platynereis dumerilii.

(A) The larvae of Platynereis dumerilii swim by coordinating the beating of cilia on the surface of the body. The cilia are arranged into several bands known as the prototroch, metatroch and paratroch I, II and III. Scale bar, 50 μm. (B) Verasztó et al. mapped the connections between the three classes of motor neurons involved in swimming. The first class of neurons produce a neurotransmitter called acetylcholine and stop the cilia in the prototroch and the three bands of the paratroch beating during the cholinergic phase. These cholinergic neurons also connect to the crescent cell in the head, which has cilia that beat alternately to the cilia in the body. The second class of neurons produce a neurotransmitter called serotonin and make the cilia in the prototroch and paratroch beat faster during the serotonergic phase. The third class of neurons – known as catecholaminergic/peptidergic neurons – form a rhythmic pacemaker system that modulates cilia activity. Figure adapted from Verasztó et al., 2017.

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Download citations (links to download the citations from this article in formats compatible with various reference manager tools)

Open citations (links to open the citations from this article in various online reference manager services)