1. Microbiology and Infectious Disease
  2. Structural Biology and Molecular Biophysics
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Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors

  1. Yang Yang
  2. Dongwei Kang
  3. Laura A Nguyen
  4. Zachary B Smithline
  5. Christophe Pannecouque
  6. Peng Zhan  Is a corresponding author
  7. Xinyong Liu  Is a corresponding author
  8. Thomas A Steitz  Is a corresponding author
  1. Yale University, United States
  2. Shandong University, China
  3. KU Leuven, Belgium
Research Article
Cite this article as: eLife 2018;7:e36340 doi: 10.7554/eLife.36340
13 data sets and 1 additional file

Data availability

Diffraction data and atomic coordinates have been deposited in the Protein Data Bank under the accession codes 6C0J, 6C0K, 6C0L, 6CGF, 6C0N, 6C0O, 6C0P, 6C0R, 6DUF, 6DUG, and 6DUH.

The following data sets were generated
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10
  11. 11
The following previously published data sets were used
  1. 1
  2. 2
    HIV-1 Reverse Transcriptase in Complex with TMC125
    1. Lansdon EB
    (2010)
    Publicly available at the RCSB Protein Data Bank (accession no. 3MEC).

Additional files

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https://cdn.elifesciences.org/articles/36340/elife-36340-supp-v1.zip

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