(A) Regenerative outgrowth of tail in high-level tyrosinase, catalase, and fetuin-b F0 mutants. While no significant difference is detected at early time points, both fetuin-b and catalase mutants display tail reduced tail regeneration compared to tyrosinase mutants at later time points (catalase vs tyrosinase, Day 4, p=0.205, Day 6, p=0.400, Day 10, p=0.111. Day 14, p=0.026, Day 18, p=0.011; fetuin-b vs tyrosinase, Day 4, p=0.450, Day 6, p=0.129, Day 10, p=0.047, Day 14, p=0.109, Day 18, 0 = 0.002, Welch’s t-test). Bars indicate standard deviation. (B) Plots of lengths of regenerate in individual tyrosinase, catalase, and fetuin-b F0 mutants at 18 days post-amputation; **=fetuin b, p=0.002, *=catalase, p=0.011. (C) Brightfield images of individual tyrosinase, catalase, and fetuin-b F0 mutants at 18 days post-amputation (dpa) showing median amount of tail regeneration at 18 dpa. Dotted line indicates the amputation plane.