A Research Advance is a short article that allows either the authors of an eLife paper or other researchers to publish new results that build on the original research paper in an important way.
The juvenile barn owl displays wide heterogeneity in tuning properties in the auditory midbrain, which is shaped during development to match the pattern of sensory statistics experienced in early life and maintained into adulthood.
A novel immunoassay for ApoB-100, the main protein component of lipoproteins, enables the development of methods to enrich extracellular vesicles from human plasma while depleting both lipoproteins and free proteins.
The chaperones Hsp70 and Sis1 collaborate to repress the heat shock response and are both transcriptional targets of the heat shock response, yet only Hsp70 acts as a negative feedback regulator of the heat shock response.
A refined analysis of the mechanisms controlling CaM kinase-1 subcellular localization in sensory neurons, a cell-autonomous process known to control nociceptive plasticity and to adjust avoidance behaviors.
The adaptor protein Grb2 is able to enhance the activity of the cytoplasmic tyrosine kinase Btk through a novel mechanism, revealing a new role for Grb2 in B-cell signaling.
Karthik Ramanadane, Márton Liziczai ... Cristina Manatschal
The structure of an NRAMP-related Al3+ transporter illustrates the evolution of a branch of a conserved protein family of metal ion transporters in plants to combat Al3+ toxicity in acidic soil.
