1. Neuroscience
  2. Structural Biology and Molecular Biophysics
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Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

  1. Ricardo Guerrero-Ferreira
  2. Nicholas MI Taylor
  3. Ana-Andreea Arteni
  4. Pratibha Kumari
  5. Daniel Mona
  6. Philippe Ringler
  7. Markus Britschgi
  8. Matthias E Lauer
  9. Ali Makky
  10. Joeri Verasdonck
  11. Roland Riek
  12. Ronald Melki
  13. Beat H Meier
  14. Anja Böckmann
  15. Luc Bousset
  16. Henning Stahlberg  Is a corresponding author
  1. University of Basel, Switzerland
  2. University of Copenhagen, Denmark
  3. CNRS, Université Paris Sud, Université Paris-Saclay, France
  4. ETH Zürich, Switzerland
  5. Roche Innovation Center Basel, Switzerland
  6. CNRS, France
  7. University of Lyon, France
Research Advance
Cite this article as: eLife 2019;8:e48907 doi: 10.7554/eLife.48907
5 data sets and 1 additional file

Data availability

Raw cryo-EM micrographs are available in EMPIAR, entry numbers EMPIAR-10323. The 3D maps are available in the EMDB, entry numbers EMD-10307 (α-Syn polymorph 2a) and EMD-10305 (α-Syn-polymorph 2b). Atomic coordinates are available at the PDB with entry numbers PDB 6SSX (α-Syn polymorph 2a) and PDB 6SST (α-Syn polymorph 2b).

The following data sets were generated
  1. 1
    aSyn polymorph 2a
    1. Guerrero-Ferreira R et al
    (2019)
    Protein Data Bank, EMD-10307.
  2. 2
    aSyn polymorph 2a
    1. Guerrero-Ferreira R et al
    (2019)
    Protein Data Bank, 6SSX.
  3. 3
    aSyn polymorph 2b
    1. Guerrero-Ferreira R et al
    (2019)
    Protein Data Bank, EMD-10305.
  4. 4
    aSyn polymorph 2b
    1. Guerrero-Ferreira R et al
    (2019)
    Protein Data Bank, 6SST.
  5. 5

Additional files

All additional files

Any figure supplements, source code, source data, videos or supplementary files associated with this article are contained within this zip.

https://cdn.elifesciences.org/articles/48907/elife-48907-supp-v1.zip

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