Learning steers the ontogeny of an efficient hunting sequence in zebrafish larvae

  1. Konstantinos Lagogiannis  Is a corresponding author
  2. Giovanni Diana
  3. Martin P Meyer  Is a corresponding author
  1. King's College London, United Kingdom

Abstract

Goal-directed behaviours may be poorly coordinated in young animals but, with age and experience, behaviour progressively adapts to efficiently exploit the animal's ecological niche. How experience impinges on the developing neural circuits of behaviour is an open question. We have conducted a detailed study of the effects of experience on the ontogeny of hunting behaviour in larval zebrafish. We report that larvae with prior experience of live prey consume considerably more prey than naive larvae. This is mainly due to increased capture success and a modest increase in hunt rate. We demonstrate that the initial turn to prey and the final capture manoeuvre of the hunting sequence were jointly modified by experience and that modification of these components predicted capture success. Our findings establish an ethologically relevant paradigm in zebrafish for studying how the brain is shaped by experience to drive the ontogeny of efficient behaviour.

Data availability

All data analyzed during this study are included in the supporting github repository.

Article and author information

Author details

  1. Konstantinos Lagogiannis

    Developmental Neurobiology, King's College London, London, United Kingdom
    For correspondence
    costaslag@gmail.com
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-9349-801X
  2. Giovanni Diana

    Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-7497-5271
  3. Martin P Meyer

    Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom
    For correspondence
    martin.meyer@kcl.ac.uk
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0001-8337-630X

Funding

Wellcome (204788/Z/16/Z)

  • Konstantinos Lagogiannis
  • Giovanni Diana
  • Martin P Meyer

The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.

Reviewing Editor

  1. Yuichi Iino, University of Tokyo, Japan

Ethics

Animal experimentation: This work was approved by the local Animal Care and Use Committee (King's College London) and was performed in accordance with the Animals (Scientific Procedures) Act, 1986, under license from the United Kingdom Home Office Licence number P9090AEFD. All primary data included in the manuscript came from the use of zebrafish larvae. All procedures were non-invasive and classified as mild according to the Animals Act 1986 and as defined by the United Kingdom Home Office, in order to minimize animal suffering. At the end of regulated procedures, animals were culled using a schedule 1 method (terminal dose of MS222).

Version history

  1. Received: January 13, 2020
  2. Accepted: August 7, 2020
  3. Accepted Manuscript published: August 10, 2020 (version 1)
  4. Version of Record published: October 15, 2020 (version 2)

Copyright

© 2020, Lagogiannis et al.

This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.

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  1. Konstantinos Lagogiannis
  2. Giovanni Diana
  3. Martin P Meyer
(2020)
Learning steers the ontogeny of an efficient hunting sequence in zebrafish larvae
eLife 9:e55119.
https://doi.org/10.7554/eLife.55119

Share this article

https://doi.org/10.7554/eLife.55119

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