Year in the x-axis refers to data collection year. Countries within sub-regions are shown in Supplementary file 1, Table 5. Studies included in this graphics are those with standard clinically relevant definitions. I.e., total cholesterol ≥150 mg/dl,≥200 mg/dl, or ≥240 mg/dl; LDL-Cholesterol ≥100 mg/dl,≥130 mg/dl, or ≥160 mg/dl; HDL-Cholesterol ≤40 mg/dl in men and ≤50 mg/dl in women; triglycerides ≥ 100 mg/dl,≥130 mg/dl,≥150 mg/dl, or ≥200 mg/dl. That is, prevalence estimates based on other definitions were excluded. Individual estimates are shown in Supplementary file 1, Table 3.