1. Epidemiology and Global Health
  2. Immunology and Inflammation
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A Global Immunological Observatory to meet a time of pandemics

  1. Michael J Mina  Is a corresponding author
  2. C Jessica E Metcalf  Is a corresponding author
  3. Adrian B McDermott
  4. Daniel C Douek
  5. Jeremy Farrar
  6. Bryan T Grenfell
  1. Harvard School of Public Health, United States
  2. Princeton University, United States
  3. National Institutes of Health, United States
  4. The Wellcome Trust, United Kingdom
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Cite this article as: eLife 2020;9:e58989 doi: 10.7554/eLife.58989

Abstract

SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory (GIO) and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise.

Article and author information

Author details

  1. Michael J Mina

    Center for Communicable Disease Dynamics, Harvard School of Public Health, Boston, United States
    For correspondence
    mmina@hsph.harvard.edu
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0002-0674-5762
  2. C Jessica E Metcalf

    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States
    For correspondence
    cmetcalf@princeton.edu
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0003-3166-7521
  3. Adrian B McDermott

    Vaccine Research Center, National Institutes of Health, Bethesda, United States
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0003-0616-9117
  4. Daniel C Douek

    Vaccine Research Center, National Institutes of Health, Bethesda, United States
    Competing interests
    The authors declare that no competing interests exist.
  5. Jeremy Farrar

    The Wellcome Trust, London, United Kingdom
    Competing interests
    The authors declare that no competing interests exist.
  6. Bryan T Grenfell

    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States
    Competing interests
    The authors declare that no competing interests exist.
    ORCID icon "This ORCID iD identifies the author of this article:" 0000-0003-3227-5909

Funding

The authors declare that there was no funding for this work.

Reviewing Editor

  1. Peter Rodgers, eLife, United Kingdom

Publication history

  1. Received: May 18, 2020
  2. Accepted: June 5, 2020
  3. Accepted Manuscript published: June 8, 2020 (version 1)
  4. Version of Record published: June 12, 2020 (version 2)

Copyright

This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

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