Crystal structures of VP40 assembled by CTD-to-CTD interactions of VP40 dimers. NTDs are colored in blue, while CTDs are in orange. (A) eVP40, C2, with insets showing the residues of the hydrophobic CTD-CTD interface (magenta) and the CTD basic patch (green). (B) sVP40, C2; (C) mVP40; (D) eVP40 linear hexamer, (E) eVP40, P62, (F) eVP40, P6422. Views are from outside the membrane surface.