Table 1. Summary of the available numbers of male and female mice from each strain and originating institution Table 2. Trait categories (parameter_group) and the number of correlated traits within these categories. Traits were meta-analysed using robumeta Table 3. We use this corrected (for correlated traits) results table, which contains each of the meta-analytic means for all effect sizes of interest, for further analyses. We further use this table as part of the Shiny App, which is able to provide the percentage differences between males and females for mean, variance and coefficient of variance (continued below) (Table 4). Summary of overall meta-analyses on the functional trait group level (GroupingTerm). Results for lnCVR, lnVR and lnRR and their respective upper and lower 95 percent CI’s, standard error and I2 values are provided. Values truncated at five decimal places for readability. Table 5. Provides an overview of meta-analysis results performed on traits that were significantly biased towards either sex. This table summarizes findings for both sexes and the respective functional trait groups. Values truncated at five decimal places for readability. Table 6. Summarizes our findings on heterogeneity due to institutions and mouse strains. These results are based on meta-analyses on sigma2 and errors for mouse strains and centres (Institutions), following the identical workflow from above. Values truncated at five decimal places for readability.