1. Cell Biology
  2. Chromosomes and Gene Expression
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DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

  1. Lorraine De Jesus Kim
  2. Larry J Friedman
  3. Marko Looke
  4. Christian K Ramsoomair
  5. Jeff Gelles  Is a corresponding author
  6. Stephen P Bell  Is a corresponding author
  1. Massachusetts Institute of Technology, United States
  2. Brandeis University, United States
  3. Howard Hughes Medical Institute, Massachusetts Institute of Technology, United States
Research Article
Cite this article as: eLife 2021;10:e65471 doi: 10.7554/eLife.65471
2 data sets and 1 additional file

Data availability

Source data for the single-molecule experiments is provided as "intervals" files that can be read and manipulated by the Matlab program imscroll, which is publicly available: https://github.com/gelles-brandeis/CoSMoS_Analysis.The source data are archived as doi: 10.5281/zenodo.4309997The sequencing data from the in vivo replication assay is archived as DOI: 10.5281/zenodo.4507881

The following data sets were generated

Additional files

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https://cdn.elifesciences.org/articles/65471/elife-65471-supp-v1.zip

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