(a) Calcium activity is recorded from an animal as it moves and then is immobilized with a paralytic drug, recording AML310_E. (b) Activity of AVAL and AVAR from (a). (c) Population activity (or its temporal derivative) from (a) is shown projected onto its first three PCs, as determined by only the immobilized portion of the recording. (d) Neural state space trajectories from (c) are shown split into moving and immobile portions, color coded by time. Scale, axes and PCs are the same in both plots. (e) Pairwise correlations of neural activity are shown as heatmaps for all neurons during movement and immobilization, sorted via a clustering algorithm. Top row is sorted to movement, bottom row is sorted to immobilization. (f) Dissimilarity between correlation matrices for moving and immobile portions of a recording are shown compared to the dissimilarity observed between correlation matrices taken at similar time windows within moving-only recordings. Dissimilarity is . Dissimilarity was measured in three moving-immobile recordings with paralytic and 11 moving-only recordings. , Welch’s unequal variance t-test. Boxes show median and interquartile range.