Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    A Forebrain Hub for Cautious Actions via the Midbrain

    Ji Zhou, Muhammad S Sajid ... Manuel A Castro-Alamancos
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation)

    James B Isbister, Andras Ecker ... Michael W Reimann
    A general and open multiscale cortical model is presented which can be used by the community to study neural coding, spike sorting, plasticity, optogenetic and extracellular stimulation, local field potential, and electroencephalography.
    1. Neuroscience

    Modeling and simulation of neocortical micro- and mesocircuitry (Part I, anatomy)

    Michael W Reimann, Sirio Bolaños-Puchet ... Srikanth Ramaswamy
    A morphologically detailed model of brain region anatomy serves as the foundation for biophysically detailed simulations and provides insights into local and inter-regional connectivity.
    1. Computational and Systems Biology
    2. Neuroscience

    Predicting human decision-making across task conditions via individuality transfer

    Hiroshi Higashi
    Encoding individual behavioral traits into a low-dimensional latent representation enables the accurate prediction of decision-making patterns across distinct task conditions.
    1. Neuroscience

    Aging: Linking neuron-glia interactions and longevity

    Michael Pokrass, Nan Hao
    Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.
    Version of Record
    Insight
    1. Neuroscience

    Dual-feature selectivity enables bidirectional coding in visual cortical neurons

    Katrin Franke, Nikos Karantzas ... Andreas Tolias
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning

    Glingna Wang, Nan Zhou ... Jai Y Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Two neuropeptides that promote blood feeding in Anopheles stephensi mosquitoes

    Prashali Bansal, Roshni Pillai ... Sonia Q Sen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Neuroscience

    Biologically informed cortical models predict optogenetic perturbations

    Christos Sourmpis, Carl CH Petersen ... Guillaume Bellec
    Multi area RNN models fitted to in-vivo cortical activity predict behavioral changes induced by optogenetic perturbations, if biologically informed connectivity constraints on the optogenetically targeted inhibitory neurons are applied.
    1. Neuroscience

    Disruption of theta-timescale spiking impairs learning but spares hippocampal replay

    Abhilasha Joshi, Alison E Comrie ... Loren M Frank
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
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Highlights

    1. Genetics and Genomics
    2. Neuroscience

    Targeting opioid addiction

    Fernanda Laezza
    1. Evolutionary Biology
    2. Neuroscience

    Taking a close look at the cerebellum

    Héloïse de Vareilles
    1. Neuroscience
    Someone typing at a laptop wearing rings and a smart watch.

    An author from the first revised Reviewed Preprint shares her experience

Senior editors

  1. Tirin Moore
    Howard Hughes Medical Institute, Stanford University, United States
  2. Panayiota Poirazi
    Foundation for Research and Technology–Hellas, Greece
  3. Michael Taffe
    University of California, San Diego, United States
  4. See more editors