Figure 3. | Pro-social behavior in rats is modulated by social experience

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Pro-social behavior in rats is modulated by social experience

Figure 3.

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University of Chicago, United States
Figure 3.
Download figureOpen in new tabFigure 3. Fostered SD rats were minimally exposed to other SD rats from birth.

This diagram indicates how many LE pups (black dots) and SD pups (red dots) were present in each litter during postnatal (P) days 0–14 (x-axis) for rats in the fostered+LE (A) and fostered+SD (B) conditions (see Figure 4). On P0–P1, two SD pups (n = 32) were transferred into each LE litter (n = 16). If both pups survived one of the two SD pups was removed at P6, leaving a single SD pup with an LE dam and LE littermates. As red dots indicate other SD pups, the number of red dots is representative of the amount of exposure each fostered SD rat had to other SD pups during their lives. Individual rats are arranged from the most exposure to SD rats (upper left in each group) to the least exposure (bottom right). Following P11, no fostered rat was exposed to other SD rats until testing. In two cases (both in the fostered+SD condition illustrated in B), the SD pup in the LE litter died at a later date (P11, P12). In these cases, an SD male who had been removed from an LE litter 5 or 7 days before was then re-added to the LE litter. Note that only one animal (upper left in B) was exposed to SD rats with his eyes open; this rat proved to be the only door-opener in the fostered+SD condition. Lines above the dots represent the strain of the dam (red: SD; black: LE).

DOI: http://dx.doi.org/10.7554/eLife.01385.006