Figure 2. | Genomic DNA transposition induced by human PGBD5

Open accessCopyright infoDownload PDFDownload figures

Genomic DNA transposition induced by human PGBD5

Figure 2.

Affiliation details

Memorial Sloan Kettering Cancer Center, United States; Weill Cornell Medical College, United States; Harvard Medical School, United States; University of Utah School of Medicine, United States; Cornell University, United States
Figure 2.
Download figureOpen in new tabFigure 2. Human piggyBac-like transposable elements have intact inverted terminal repeat sequences similar to the T. ni piggyBac transposon.

(A) Chromosome ideogram representing the distribution of annotated piggyBac-like elements in the human genome (version hg19). (B) Multiple sequence alignment of the piggybac inverted terminal repeat (ITR) sequence with the consensus ITR sequences of the MER75 and MER85 families of piggyBac-like elements. (C) Chromosome ideogram representing the distribution of piggyBac-like elements annotated in the human genome (version hg19) with TTAA target site duplication as well as ITR sequences aligning with the consensus (intact ITRs).

DOI: http://dx.doi.org/10.7554/eLife.10565.005