Figure 6. | Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

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Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

Figure 6.

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City College of the City University of New York, United States; New York University School of Medicine, United States; Mayo Clinic, United States
Figure 6.
Download figureOpen in new tabFigure 6. Electric field predicted with individually calibrated models under 1 mA stimulation.

(A) Summary of electric field magnitudes for all subjects. The four different configurations of stimulation electrodes in Subject P014 are indicated as P014A–P014D. Also shown are values for a few stimulation montages commonly used in clinical trials simulated for Subject P03 (M1–SO, C3–C4, Cz–Oz). Whiskers indicate the maximal and minimal values of electric field magnitudes observed across the entire brain, and box indicates the 5% and 95% percentile across locations. Line inside the box indicates median value. (B) Electric field magnitudes as a function of depth, measured as the distance from the origin of the MNI coordinate system and normalized by diameter of the brain. Maximal field value is achieved at the cortical surface, which is approximately at distance of 0.55 (distance was divided by brain diameter in each MNI dimension). Locations exceeding 0.55 indicate mostly brain stem and cerebellum. Maximal value for each depth is indicated in green. (C) Summary of maximum for each of the 10 subjects and montages shown in (A) as a function of depth.

DOI: http://dx.doi.org/10.7554/eLife.18834.008