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    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Study reveals intricate molecular detail of human DNA repair process

    Researchers have revealed the fundamental mechanisms underlying homologous recombination – one of the main DNA repair pathways in human cells.
    1. Epidemiology and Global Health

    Asymptomatic transmission may explain resurgence of whooping cough

    A new study of mothers and infants in Lusaka, Zambia, reveals that people without symptoms can still spread pertussis (or whooping cough), highlighting the need for better disease surveillance.
    1. Neuroscience

    New fruit fly resource reveals nerve circuits that control flight and courtship

    Researchers have created a library of genetically engineered fruit flies linked to individual neurons in the nerve cord to characterise the circuits controlling wing motion.
  1. eLife named among winners of inaugural Crossref Metadata Excellence Awards

    eLife has been announced as a winner in the first Crossref Metadata Awards, recognising its commitment to high-quality metadata in the research it publishes.
  2. More than 100 institutions and funders confirm recognition of eLife papers, signalling support for open science

    Conversations with research organisations offer reassurance to researchers and highlight growing momentum behind fairer, more transparent models of scientific publishing and assessment.
    1. Neuroscience

    Negative expectations have stronger and longer-lasting effects on pain than positive ones

    A new study finds that nocebo effects, where people expect a negative outcome from treatment, are more powerful and persistent than placebo effects, with implications for patient-practitioner communication.
    1. Cell Biology
    2. Cancer Biology

    3D cell cultures provide new insights on lung cancer treatment response

    Researchers have shown that activation of the protein YAP, which helps tumours grow, differs between two- and three-dimensional culture models, pointing to more predictive systems for testing cancer therapies.
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    Viral ‘backbone’ underlies variation in rotavirus vaccine effectiveness

    A new study has shown that full-genome differences between rotavirus strains influence vaccine effectiveness, highlighting the need for a broader approach to vaccine design.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Hidden virus harboured by fruit flies may influence experimental accuracy

    A new study suggests the presence of Nora virus in laboratory strains of Drosophila fruit flies influences their resilience to stress and bacterial infection and can confound experimental studies of ageing.
  3. Media Coverage: January roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in January 2025, including CBC, India Education Diary and LiveScience.