Hannah M Oberle, Alexander N Ford ... Pierre F Apostolides
Optogenetic and electrophysiological experiments show how a behaviorally relevant 'feedback' pathway from auditory cortex controls neural activity in the inferior colliculus, an auditory midbrain region important for processing complex time-varying sounds such as speech.
The inferior colliculus integrates auditory and cognitive functions, playing critical roles in sensory prediction, reward processing, and decision-making beyond its traditional role as a sensory relay.
David Goyer, Marina A Silveira ... Michael T Roberts
VIP neurons are a novel class of inferior colliculus stellate neurons that project to long-range auditory and non-auditory targets and integrate inputs from the auditory brainstem and contralateral IC.
Juan Carlos Boffi, Brice Bathellier ... Robert Prevedel
Bespoke volumetric calcium imaging, validated with neuropixels recordings, evidence a population code for sound azimuth at the dorsal cortex of the inferior colliculus, with a contribution of noise correlations.
Robust and wide-spread locomotion-related neural signals, revealed in the mouse auditory midbrain, suggest that integrating movement-related information is an essential aspect of midbrain sound processing.
A spatial analysis of auditory and non-auditory properties of excitatory and inhibitory neurons in the mouse dorsal inferior colliculus defines the border between the lateral and the dorsal cortex.
Alexandria MH Lesicko, Christopher F Angeloni ... Maria N Geffen
A specific neuronal pathway within the auditory system represents information about the statistical prediction and error for incoming sounds, thereby contributing to efficient representation of complex sounds and sound streams in the brain.
Deactivation of one side of the auditory midbrain while recording in the other shows that the two sides cooperate in processing frequency and in enhancing the encoding of sound level.