Cholecystokinin-positive neural projection from entorhinal cortex to lateral amygdala modulates the long-term potentiation of auditory-evoked potential in lateral amygdala and underlies the formation of trace fear memory.
Discrimination of predictive and non-predictive fear stimuli requires plasticity in the lateral amygdala that is regulated by midbrain dopamine neurons.
Mohammed Mostafizur Rahman, Sonal Kedia ... Sumantra Chattarji
Activation of the same glutamate receptor in the lateral amygdala gives rise to distinct effects on specific versus indiscriminate fear by modulating intrinsic excitability and synaptic plasticity.
SOM+ GABAergic neuronal signaling and inhibitory transmission in the central lateral amygdala is regulated by TMEM16B, which is also involved in fear and anxiety-like behaviors.
A data-driven exploration of amygdala microstructure captures this region's subnuclear structure and dissociates its cortical functional connectivity profiles.
Behavioral analyses and an optogenetic approach reveal an existence of GR-mediated metaplasticity in the LA and its link with adaptive fear response to auditory cues in a stressful condition.
Human hippocampal connectivity to network afferents varies continuously with the phase of the local theta oscillation, confirming a putative mechanism by which neural oscillations modulate human hippocampal function.
Timothy P O'Leary, Kaitlin E Sullivan ... Mark S Cembrowski
Basolateral amygdala excitatory neurons are a highly heterogenous collection of neurons that spatially covary in molecular, cellular, and circuit properties.
Variations in the frequency of theta brain waves enable a single network of brain regions to generate appropriate responses to stimuli with different kinds of emotional value.