479 results found
    1. Neuroscience

    The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the mouse lateral amygdala via cholecystokinin

    Hemin Feng, Junfeng Su ... Jufang He
    Cholecystokinin-positive neural projection from entorhinal cortex to lateral amygdala modulates the long-term potentiation of auditory-evoked potential in lateral amygdala and underlies the formation of trace fear memory.
    1. Neuroscience

    A genetic link between discriminative fear coding by the lateral amygdala, dopamine, and fear generalization

    Graham L Jones, Marta E Soden ... Larry S Zweifel
    Discrimination of predictive and non-predictive fear stimuli requires plasticity in the lateral amygdala that is regulated by midbrain dopamine neurons.
    1. Neuroscience

    Activation of the same mGluR5 receptors in the amygdala causes divergent effects on specific versus indiscriminate fear

    Mohammed Mostafizur Rahman, Sonal Kedia ... Sumantra Chattarji
    Activation of the same glutamate receptor in the lateral amygdala gives rise to distinct effects on specific versus indiscriminate fear by modulating intrinsic excitability and synaptic plasticity.
    1. Neuroscience

    TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala

    Ke-Xin Li, Mu He ... Lily Yeh Jan
    SOM+ GABAergic neuronal signaling and inhibitory transmission in the central lateral amygdala is regulated by TMEM16B, which is also involved in fear and anxiety-like behaviors.
    1. Neuroscience

    From histology to macroscale function in the human amygdala

    Hans Auer, Donna Gift Cabalo ... Jessica Royer
    A data-driven exploration of amygdala microstructure captures this region's subnuclear structure and dissociates its cortical functional connectivity profiles.
    1. Neuroscience

    Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala

    Linnaea E Ostroff, Emanuela Santini ... Eric Klann
    A diverse assortment of mRNAs are present in projection axons in the adult forebrain and their translation is associated with new memory formation.
    1. Neuroscience

    Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress

    Ran Inoue, Kareem Abdou ... Hisashi Mori
    Behavioral analyses and an optogenetic approach reveal an existence of GR-mediated metaplasticity in the LA and its link with adaptive fear response to auditory cues in a stressful condition.
    1. Neuroscience

    Human hippocampal responses to network intracranial stimulation vary with theta phase

    Sarah M Lurie, James E Kragel ... Joel L Voss
    Human hippocampal connectivity to network afferents varies continuously with the phase of the local theta oscillation, confirming a putative mechanism by which neural oscillations modulate human hippocampal function.
    1. Neuroscience

    Extensive and spatially variable within-cell-type heterogeneity across the basolateral amygdala

    Timothy P O'Leary, Kaitlin E Sullivan ... Mark S Cembrowski
    Basolateral amygdala excitatory neurons are a highly heterogenous collection of neurons that spatially covary in molecular, cellular, and circuit properties.
    1. Neuroscience

    Different types of theta rhythmicity are induced by social and fearful stimuli in a network associated with social memory

    Alex Tendler, Shlomo Wagner
    Variations in the frequency of theta brain waves enable a single network of brain regions to generate appropriate responses to stimuli with different kinds of emotional value.

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