1,724 results found
    1. Neuroscience

    Nonlinear transient amplification in recurrent neural networks with short-term plasticity

    Yue Kris Wu, Friedemann Zenke
    The interplay of recurrent excitation and short-term plasticity enables nonlinear transient amplification, an ideal mechanism for selective amplification, pattern completion, and pattern separation in recurrent neural networks.
    1. Neuroscience

    Unsupervised changes in core object recognition behavior are predicted by neural plasticity in inferior temporal cortex

    Xiaoxuan Jia, Ha Hong, James J DiCarlo
    Temporal continuity-induced plasticity in individual neurons of inferior temporal cortex builds neural representations that underlie robust core object recognition behavior.
    1. Genetics and Genomics
    2. Neuroscience

    High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans

    Qiaochu Li, Daniel-Cosmin Marcu ... Karl Emanuel Busch
    Chronic excitation of the Caenorhabditis elegans oxygen-sensing neurons alters calcium homeostasis to accelerate the decline of neural plasticity with age.
    1. Neuroscience

    Oligodendrocyte-mediated myelin plasticity and its role in neural synchronization

    Sinisa Pajevic, Dietmar Plenz ... R Douglas Fields
    A biologically plausible model of myelin plasticity demonstrates how oligodendrocytes can selectively adjust conduction delays in axon bundles to allow robust communication between brain regions through long-range synchronization.
    1. Computational and Systems Biology
    2. Neuroscience

    Stable task information from an unstable neural population

    Michael E Rule, Adrianna R Loback ... Timothy O'Leary
    Analysis and modelling of sensorimotor neural activity shows how ongoing plasticity and appropriately tuned weights can cope with substantial ongoing changes in the neural code.
    1. Neuroscience

    The generation of cortical novelty responses through inhibitory plasticity

    Auguste Schulz, Christoph Miehl ... Julijana Gjorgjieva
    Inhibitory synaptic plasticity provides a flexible and biologically plausible circuit mechanism to detect the novelty of bottom-up stimuli and to generate stimulus-specific adaptation.
    1. Neuroscience

    Evolution of neural activity in circuits bridging sensory and abstract knowledge

    Francesca Mastrogiuseppe, Naoki Hiratani, Peter Latham
    Gradient-descent synaptic plasticity applied to neuroscience categorization tasks captures the behaviour of common neural activity measures (category and context selectivity, correlation, asymmetry) reported in experiments, and makes novel experimental predictions.
    1. Neuroscience

    Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation

    Sebastian C Holst, Alexandra Sousek ... Hans-Peter Landolt
    Multi-modal imaging, genetic and behavioral findings in humans and mice revealed that metabotropic glutamate receptors of subtype 5 contribute to the molecular machinery keeping track of sleep need and coping with physiological and behavioral consequences of sleep loss, pointing to novel targets for improved wakefulness and sleep.
    1. Neuroscience

    Neural learning rules for generating flexible predictions and computing the successor representation

    Ching Fang, Dmitriy Aronov ... Emily L Mackevicius
    A recurrent network using a simple, biologically plausible learning rule can learn the successor representation, suggesting that long-horizon predictions are computations that are easily accessible in neural circuits.
    1. Neuroscience

    Increasing stimulus similarity drives nonmonotonic representational change in hippocampus

    Jeffrey Wammes, Kenneth A Norman, Nicholas Turk-Browne
    Hippocampal learning in dentate gyrus follows a U-shaped function, with moderate, but not high or low, overlap between representations leading to differentiation of neural patterns.

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