A cystic fibrosis (CF) lung microbiome-informed in vitro polymicrobial system allows for a mechanistic understanding of community-specific tolerance of Pseudomonas aeruginosa to a front-line CF antimicrobial.

The growth environment driven ratio of ATP to growth rate, called absolute growth, determines the final population composition of Staphylococcus aureus and Pseudomonas aeruginosa when in co-culture.

Diverse LXG toxins delivered by the Esx pathway function as mediators of contact-dependent interbacterial antagonism within and between Gram-positive bacterial species.

The upper airway commensal, Neisseria cinerea, competes with related species using a T6SS, with antagonism modulated by the spatial dynamics of attacker and prey strains growing in a mixed community.

Structural and functional analyses identify a new family of bifunctional cell-wall-targeting type VI secretion system (T6SS) effectors and a surface-charge-engineering strategy that expands T6SS activity against Gram-positive cells.

Pseudomonas aeruginosa coordinates invasion and destruction of Staphylococcus aureus communities by modulating single-cell and collective motility.

DNA uptake and recombination in pneumococcus are highly efficient and independent of the cell-cycle or genetic location of the transformed allele, but limited to maximally 50% of the population.

The characterization of ancient B19V and HBV genotype A4 viruses circulating during Colonial epidemics provides new insights into the pathogens that were introduced to the Americas after the European colonization.

Microfluidic culture and high-resolution 3-D microscopy establish that bacteriophages trapped in the outer matrix layers of a bacterial biofilm remain active and can prevent colonization of the biofilm by newly arriving bacteria.