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    1. Cell Biology
    2. Neuroscience

    Activity-dependent CO2 production in the axon triggers opening of Connexin32 in the Schwann cell paranode

    Jack Butler, Lowell Mott ... Nicholas Dale
    Gaseous CO2 acts as a neuron to glia messenger in peripheral myelin to trigger opening of Schwann Cell Cx32 hemichannels in response to axonal action potential propagation.
    1. Cell Biology

    CROP2, a Retriever-PROPPIN Complex Mediating Protein Export from Endosomes to the Plasma Membrane

    Maria Giovanna De Leo, Andreas Mayer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Non-canonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy

    Hao Chen, Haocheng Wang ... Jiou Wang
    Minimally disruptive genetic code expansion enables faithful, site-specific labeling of G3BP1 and TDP-43, revealing native stress granule dynamics and ALS-linked protein behavior in live cells.
    1. Cell Biology

    Nuclear export modulates TDP-43 phase transition and cytoplasmic aggregation

    Natalie Chin, Qi Zhang ... Yihong Ye
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Cell Biology

    Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair

    James S White, Junmin Hua ... Andrea Page-McCaw
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Membrane contact site resident PTP1B limits superoxide production by suppressing a Syk-Shc1-Phagocyte Oxidase relay

    Minhyoung Lee, Haggag S Zein ... Gregory D Fairn
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Wunen(s) help navigate Primordial Germ Cells by attenuating Hedgehog signaling

    Amrita Roy, Adheena Elsa Roy ... Girish Deshpande
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation

    Priyanka Gajwani, Li Wang ... Jalees Rehman
    1. Cell Biology
    2. Neuroscience

    A Single-Cell Signaling Atlas of Spinal Cord BDNF Responses Reveals Determinants Beyond Receptor Expression

    Jonathon M Sewell, Autumn C Bissett ... Chris D Deppmann
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis

    Changle Zhao, Yongxun Chen ... Jing Wei
    Desert Hedgehog signaling promotes stem Leydig cell differentiation through a Ptch2-Gli1-Sf1 regulatory axis in Nile tilapia.
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