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    1. Cell Biology
    2. Developmental Biology

    Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL

    Dong Luo, Jing Zheng ... Xinjun Zhang
    RSPO-ZNRF3/RNF43 specifically regulates the degradation of FZD5/8 under Wnt stimulation independently of DVL.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during Shigella infection

    Ana Teresa López-Jiménez, Dominik Brokatzky ... Serge Mostowy
    High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.
    1. Cell Biology

    Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

    Claire Masson, Cyril Scandola ... Anita Eckly
    Megakaryocytes form a 3D cage of laminin and collagen IV that stabilizes them within their vascular niche, while β1/β3 integrins and MMP are key regulators that assist megakaryocyte maturation and intravasation.
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Calcium transfer from the ER to other organelles for optimal signaling in Toxoplasma gondii

    Zhu-Hong Li, Beejan Asady ... Silvia NJ Moreno
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner

    Yoshihisa Kaizuka, Rika Machida
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology

    The Multifaceted Role of EXOC6A in Ciliogenesis

    Te-Lin Lin, Chien-Ting Wu, Tang K Tang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline

    Sara C Sebag, Tate Neff ... Ling Yang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance

    Xue Chen, Deng Pan ... Yanrui Yang
    Endophilin A1 at postsynaptic sites promotes inhibitory postsynaptic organization through interaction with gephyrin to maintain E/I balance, which is essential for the suppression of epilepsy susceptibility.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

    Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
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