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    1. Developmental Biology
    2. Cell Biology

    Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

    Benjamin Mattes et al.
    Wnt signaling regulates its effective signaling range by controlling Wnt ligand transport on signaling filopodia within vertebrate tissues.
    1. Cell Biology
    2. Computational and Systems Biology

    Multiple inputs ensure yeast cell size homeostasis during cell cycle progression

    Cecilia Garmendia-Torres et al.
    Yeast cell size homeostasis is not controlled by a G1-specific mechanism alone but is likely to be an emergent property resulting from the integration of several mechanisms that coordinate cell and bud growth with division.
    1. Cell Biology
    2. Computational and Systems Biology

    A quantitative approach for analyzing the spatio-temporal distribution of 3D intracellular events in fluorescence microscopy

    Thierry Pécot et al.
    QuantEv is a fully automatic and semi-parametric method that allows quantitative analysis of the spatio-temporal distribution of complex molecular trafficking objects at the scale of the whole cell.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Timing of ESCRT-III protein recruitment and membrane scission during HIV-1 assembly

    Daniel S Johnson et al.
    During viral assembly, ESCRTIII and VPS4 are recruited after most of the HIV-1 membrane is bent but disappear prior to scission of the virion from the cell.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2

    Melissa Kane et al.
    1. Cell Biology

    Cortical dynein pulling mechanism is regulated by differentially targeted attachment molecule Num1

    Safia Omer et al.
    Dynein-dependent microtubule-cortex interactions – "side-on" versus "end-on" pulling – are regulated by cortical ER and mediated by distinct pools of cortical anchor that are differentially localized along the cell periphery.
    1. Cell Biology
    2. Neuroscience

    Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

    Kentarou Baba et al.
    Shootin1a, through its spatially regulated phosphorylation within growth cones, mediates the gradient reading and mechanoresponse for netrin-1-induced axon guidance.
    1. Cell Biology

    Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases

    Yi Xiong et al.
    Genetic mouse models show that hepatic NIK and IKKα inhibit hepatocyte proliferation and liver regeneration in part by inhibiting the JAK2/STAT3 pathway.
    1. Cell Biology
    2. Neuroscience

    Hypoxia-inducible factor cell non-autonomously regulates C. elegans stress responses and behavior via a nuclear receptor

    Corinne L Pender, H Robert Horvitz
    The hypoxia-inducible factor HIF drives transcription of the gene cyp-36A1, which encodes a cytochrome P450 enzyme that acts via a putative intercellular signal to regulate the nuclear receptor NHR-46 and consequently stress resistance and behavior.
    1. Cell Biology

    Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription

    Marco Novais-Cruz et al.
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