Browse our latest Cell Biology articles

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    1. Cell Biology
    2. Immunology and Inflammation

    Tongue immune compartment analysis reveals spatial macrophage heterogeneity

    Ekaterini Maria Lyras et al.
    The tongue is a unique barrier organ, which is constantly exposed to environmental pathogens, and therefore is expected to host an immune cell network ensuring local immune defence, which we characterised during development, health, and disease.
    1. Cell Biology

    Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami

    Shimaa A Abdellatef et al.
    A pair of microtubules, ensembles of oppositely oriented axonemal dyneins, and inter-microtubule crosslinkers are the minimum components needed for oscillation and repetitive bending motions.
    1. Cell Biology

    Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α

    Silvia Gómez-Puerta et al.
    Development of a live single-molecule imaging approach to visualize XBP1 mRNAs, which are recruited for translation on the ER and efficiently spliced in the absence of large IRE1α foci.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers

    Vladislav Belyy et al.
    Stress sensors in the membrane of the endoplasmic reticulum respond to the accumulation of unfolded proteins by briefly forming small phosphorylation-competent oligomers and dissolving back into active dimers.