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    1. Cell Biology

    Engineered Migrasomes: Harnessing Core Migrasome Machinery and Hypotonic Shock to Develop a Robust and Thermally Stable Vaccine Platform

    Dongju Wang, Haifang Wang ... Zhihua Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells

    Scott D Zawieja, Grace A Pea ... Michael J Davis
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

    Roya Pournejati, Jessica M Huang ... Oscar Vivas
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    FMRP Regulates Neuronal RNA Granules Containing Stalled Ribosomes, Not Where Ribosomes Stall

    Jewel T-Y Li, Mehdi Amiri ... Wayne S Sossin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Dominant spinal muscular atrophy linked mutations in the cargo binding domain of BICD2 result in altered interactomes and dynein hyperactivity

    Hannah Neiswender, Rajalakshmi Veeranan-Karmegam ... Graydon B Gonsalvez
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation

    Abhishek Kumar, Keiichiro Tanaka, Martin A Schwartz
    Focal adhesion derived p130Cas condensates regulate translation in an adhesion strength dependent manner.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway

    Lan Yao, Wanwan Zhang ... Kuntong Jia
    MYL3 is identified as a novel receptor enabling nervous necrosis virus (NNV) entry via macropinocytosis, revealing a therapeutic target for combating NNV outbreaks in aquaculture.
    1. Cell Biology

    Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

    Raymond Laboy, Marjana Ndoci ... Adam Antebi
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology

    SMC5/6-Mediated Plasmid Silencing is Directed by SIMC1-SLF2 and Antagonized by LT

    Martina Oravcová, Minghua Nie ... Michael N Boddy
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology

    The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy

    Yutaro Hama, Yuko Fujioka ... Nobuo N Noda
    AlphaFold-guided in vitro and in vivo analyses establish the mechanism of ULK complex formation and provide a structural basis for understanding its role in mammalian autophagy initiation.
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