Browse our latest Cell Biology articles

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    1. Cell Biology
    2. Neuroscience

    Desmosomal connectomics of all somatic muscles in an annelid larva

    Sanja Jasek, Csaba Verasztó ... Gáspár Jékely
    Volume-EM reconstruction of a whole-body desmosomal connectome including all muscles and their desmosomal partners in a Platynereis larva provides a detailed view of the organisation of the entire locomotor system in an animal.
    1. Cell Biology
    2. Neuroscience

    Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers

    Shenjie Wu, Nancy C Hernandez Villegas ... Randy Schekman
    A pathway of unconventional secretion for alpha-synuclein, a protein which may spread in the brain as part of the pathology of Parkinson’s disease.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle

    Hirotaka Araki, Shinjiro Hino ... Mitsuyoshi Nakao
    Lysine-specific demethylase-1 acts as an epigenetic barrier against glucocorticoid-induced atrophy and exercise-induced hypertrophy in skeletal muscle.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)

    Michael J Rale, Brianna Romer ... Sabine Petry
    An evolutionarily conserved protein sequence present in diverse species like yeast, frogs, chickens, and humans binds a well-known template for microtubule nucleation, the gamma-tubulin ring complex, activating and enhancing its ability to nucleate microtubules, even under low tubulin concentrations.
    1. Cell Biology
    2. Developmental Biology

    Trisomy 21 induces pericentrosomal crowding delaying primary ciliogenesis and mouse cerebellar development

    Cayla E Jewett, Bailey L McCurdy ... Chad G Pearson
    Trisomy 21, the genetic cause of Down syndrome, produces elevated centrosome protein levels reducing intracellular trafficking to and from the centrosome thereby delaying primary ciliogenesis, ciliary signaling, and mouse cerebellar development.