Browse our latest Cell Biology articles

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    1. Cell Biology

    Loss of SPNS1, a lysosomal transporter, in the nervous system causes dysmyelination and white matter dysplasia

    Yoshinobu Ichimura, Yuki Sugiura ... Masaaki Komatsu
    1. Cell Biology

    Involvement of TRPV4 in temperature-dependent perspiration in mice

    Makiko Kashio, Sandra Derouiche ... Makoto Tominaga
    TRPV4 and ANO1 are co-expressed in the sweat glands of mouse food pads and found to be involved in perspiration, suggesting that local temperature sensation through TRPV4 could control seating.
    1. Cell Biology

    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease

    Yuki Date, Yukiko Sasazawa ... Shinji Saiki
    Lysosomal clustering around the microtubule-organizing centre would be a promising therapeutic strategy for Parkinson's disease.
    1. Cancer Biology
    2. Cell Biology

    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

    Savvas Nikolaou, Amelie Juin ... Laura M Machesky
    Macropinocytosis of the signalling receptor LPAR1, by an actin and CYRI-B-dependent mechanism, impacts on progression and spread of pancreatic cancer in a mouse model.
    1. Cell Biology

    A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture

    Rachel Pudlowski, Lingyi Xu ... Jennifer T. Wang
    1. Cell Biology
    2. Physics of Living Systems

    Cell Migration: Pump up the volume

    Qin Ni, Sean X Sun
    An influx of water molecules can help immune cells called neutrophils to move to where they are needed in the body.
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    1. Cell Biology
    2. Physics of Living Systems

    Neutrophils actively swell to potentiate rapid migration

    Tamas L Nagy, Evelyn Strickland, Orion D Weiner
    Actin-independent water influx complements actin-driven cytoskeletal forces to potentiate chemoattractant-induced migration in primary human neutrophils.
    1. Cell Biology
    2. Developmental Biology

    A CDK1 phosphorylation site on Drosophila PAR-3 regulates neuroblast polarisation and sensory organ formation

    Nicolas Loyer, Elizabeth KJ Hogg ... Jens Januschke
    PAR-3/Baz function is regulated by CDK1 in asymmetrically dividing cells in the central and peripheral nervous system of Drosophila revealing direct regulation of cell polarity by the cell cycle machinery in the context of cell fate specification.