Merve Deniz Abdusselamoglu, Elif Eroglu ... Jürgen A Knoblich
Odd-paired (opa) is required for the progression of temporal patterning in Drosophila neural progenitors to regulate temporal identities via an incoherent feed-forward loop.
Single-cell splicing of a conserved neuronal kinase is established by a combinatorial code of fate-determining transcription factors and neuronal RNA binding proteins, with different combinations in different neuron types.
Jesús Rodriguez Curt, Behzad Yaghmaeian Salmani, Stefan Thor
The expansion of the anterior Drosophila CNS is driven by increased progenitor generation and prolonged proliferation, mediated by brain-restricted genes and the PRC2.
Samuel Andrew Malone, Georgios E Papadakis ... Paolo Giacobini
Mouse in vivo and in vitro analysis and human genetic screening highlight the role of anti-Müllerian hormone (AMH) signaling in GnRH neuronal development and function, and identify mutations in AMH and AMHR2 in CHH patients.
Anchoring of proteins to the cell membrane through the glycosylphosphatidylinositol (GPI) anchor is critical for the survival of the cells that will give rise to the brain and face.
Chick optic fissure closure is a powerful new model system for epithelial fusion and has revealed Netrin-1 as a conserved and essential mediator of tissue fusion in multiple contexts.
Genes implicated in the control of mammalian puberty function as components of a molecular clock that determines the timing of sexual differentiation in the C. elegans nervous system.
Ezh2 and Arid1a oppose each other to control expression of Cdkn2a to coordinate tooth furcation development and ultimately determine the number of roots in mouse molars.
