Browse our latest Immunology and Inflammation articles

Loss of class A scavenger receptor MARCO results in elevated lung Ace expression and elevated plasma aldosterone concentrations in male mice, demonstrating an endocrine function of this immune scavenger receptor.

PLSCR1 is an IFN-λ-stimulated gene that enhances IFN-λR1 expression at both transcriptional and protein level, highlighting the potential for targeting PLSCR1 pathways in anti-influenza therapy.

Combining scientific rigour and drug development experience to map out a route to novel treatments for Trained Immunity-dependent diseases.

Immunoglobulin M has other functions beyond antibody class switching that have implications in asthma treatment.

Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.

BOAS is a platform for building multivalent viral protein immunogens without a scaffold, such as a nanoparticle, to elicit broad influenza vaccine responses.

A holistic narrative describes how extracellular matrices regulate various aspects of the entire leukocyte journey from blood to inflamed tissue, and the subsequent functional impacts on leukocyte and tissue fates.