Browse our latest Immunology and Inflammation articles

Both adaptive and innate immune memory responses have been described in gamma delta T cells, yet the mechanisms, the ligands and the gamma delta T cell subsets generating memory responses have remain to be explored.

Systemic neutrophils do not respond to laser-induced photoreceptor damage despite the robust response from resident microglia.

Regulatory T cell expression of layilin mediates adhesion in skin, which acts to attenuate their suppressive capacity.

Interferon-γ and prostaglandin E2 signaling oppose each other to determine the balance between two distinct TNF-induced inflammatory gene expression programs relevant for rheumatoid and immune checkpoint inhibitor-induced arthritis.

Dysregulated myelopoiesis is identified as a driver of nutritionally acquired immunodeficiency that persists after refeeding and nutritional recovery, indicating exposure to food scarcity may be an immunologic risk factor.

β-Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

CCR4 expression in Tregs is critical for limiting proinflammatory Th1 cell-mediated immune responses and atherosclerosis by maintaining the suppressive and migratory functions of Tregs.

Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.