Jingbo Kan, Adrian Morales-Amador ... Sean F Brady
Oxydifficidin presents potent activity against multidrug-resistant Neisseria gonorrhea with a new mode of action, which opens a new avenue for potentially addressing antibiotic resistant gonorrhea.
IFN-β-induced WTAP phase transition bridges STAT1 and MTC, which orchestrates m6A dynamics on ISG mRNAs to suppress excessive immune response and sustain immune homeostasis.
Marc-Antoine Guery, Sukai Ceesay ... Antoine Claessens
Household clustering and seasonal parasite dynamics highlight the need to target asymptomatic carriers for community-based malaria elimination strategies.
Precise protein quality control in the endoplasmic reticulum is crucial for Cryptococcus neoformans pathogenicity by modulating glycoprotein processing and extracellular vesicle-mediated transport of virulence factors.
The SUN1-ALLAN complex serves as a nuclear envelope–spanning tether that coordinates the segregation of a bipartite microtubule organising center (MTOC) during the unusual mitosis of Plasmodium.