Browse our latest Microbiology and Infectious Disease articles

Page 13 of 171
    1. Microbiology and Infectious Disease

    Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA-assisted uptake and ribosomal protein RplL sensitivity

    Jingbo Kan, Adrian Morales-Amador ... Sean F Brady
    Oxydifficidin presents potent activity against multidrug-resistant Neisseria gonorrhea with a new mode of action, which opens a new avenue for potentially addressing antibiotic resistant gonorrhea.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Phase transition of WTAP regulates m6A modification of interferon-stimulated genes

    Sihui Cai, Jie Zhou ... Jun Cui
    IFN-β-induced WTAP phase transition bridges STAT1 and MTC, which orchestrates m6A dynamics on ISG mRNAs to suppress excessive immune response and sustain immune homeostasis.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Household clustering and seasonal genetic variation of Plasmodium falciparum at the community-level in The Gambia

    Marc-Antoine Guery, Sukai Ceesay ... Antoine Claessens
    Household clustering and seasonal parasite dynamics highlight the need to target asymptomatic carriers for community-based malaria elimination strategies.
    1. Microbiology and Infectious Disease

    Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans

    Catia Mota, Kiseung Kim ... Hyun Ah Kang
    Precise protein quality control in the endoplasmic reticulum is crucial for Cryptococcus neoformans pathogenicity by modulating glycoprotein processing and extracellular vesicle-mediated transport of virulence factors.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

    Supratim Pradhan, Dhruba Dhar ... Budhaditya Mukherjee
    Nutritional adaptations in Leishmania donovani enable persistent antimony resistance and reduced Amphotericin-B effectiveness by selectively exploiting host lipids and limiting cholesterol mobilization.
    1. Microbiology and Infectious Disease

    Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria

    Yogita Kapoor, Himani Khurana ... Vinay Kumar Nandicoori
    A novel function of Wag31 in membrane tethering and molecular dissection of the functions of its N- and C-terminal domains.
    1. Microbiology and Infectious Disease

    Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation

    Simone Margaard Offersen, Signe Adamberg ... Anders Brunse
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Secretory leukocyte protease inhibitor influences periarticular joint inflammation in Borrelia burgdorferi-infected mice

    Qian Yu, Xiaotian Tang ... Erol Fikrig
    Secretory leukocyte protease inhibitor suppresses Borrelia burgdorferi infection-induced periarticular inflammation in mice by maintaining anti-protease–protease balance.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium berghei

    Mohammad Zeeshan, Igor Blatov ... Rita Tewari
    The SUN1-ALLAN complex serves as a nuclear envelope–spanning tether that coordinates the segregation of a bipartite microtubule organising center (MTOC) during the unusual mitosis of Plasmodium.