Browse our latest Microbiology and Infectious Disease articles

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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The Mycobacterium tuberculosis complex pangenome is small and shaped by sub-lineage-specific regions of difference

    Mahboobeh Behruznia, Maximillian Marin ... Conor J Meehan
    The accessory genome of Mycobacterium tuberculosis is small, but differences in gene content are found both between and within lineages.
    1. Microbiology and Infectious Disease

    Spatial integration of sensory input and motor output in Pseudomonas aeruginosa chemotaxis through colocalized distribution

    Zhengyu Wu, Maojin Tian ... Junhua Yuan
    In Pseudomonas aeruginosa, the chemoreceptor cluster and flagellar motor colocalize at the same cell pole through FlhF anchoring, preventing cross-pathway signaling interference between chemotaxis and c-di-GMP regulation.
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    Inferring variant-specific effective reproduction numbers from combined case and sequencing data

    Marlin D Figgins, Trevor Bedford
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow

    Ilona P Foik, Runhang Shu ... Albert Siryaporn
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cancer Biology
    2. Microbiology and Infectious Disease

    The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling in human papillomavirus type 16-infected cervical cancer cells

    Haibin Liu, Lulu Yu ... Zhi-Ming Zheng
    A newly discovered long noncoding RNA lnc-FANCI-2 suppresses RAS signaling to modulate Akt and Erk1/2 phosphorylation in high-risk HPV cervical cancer, consequently regulating HPV carcinogenesis.
    1. Microbiology and Infectious Disease

    Temporal dynamics of viral fitness and the adaptive immune response in HCV infection

    Melanie Rose Walker, Preston Leung ... Rowena A Bull
    Early immune pressure and co-occurring mutations drive changes in hepatitis C virus fitness and evolution, revealing key dynamics in the establishment of chronic infection.
    1. Microbiology and Infectious Disease

    Multi-omics investigation of spontaneous T2DM macaque emphasizes gut microbiota could up-regulate the absorption of excess palmitic acid in the T2DM progression

    Xu Liu, Yuchen Xie ... Jing Li
    Gut dysbiosis and specific microbiota composition promoted the absorption of excess palmitic acid in the ileum, driving its accumulation in the serum.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell

    David Jones, Hugo Belda ... Moritz Treeck
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Convincing
    1. Microbiology and Infectious Disease

    A novel mechanism for bacterial sporulation based on programmed peptidoglycan degradation

    Carlos A Ramírez Carbó, Oihane Irazoki ... Beiyan Nan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Innate immunity and training to subvert original antigenic sin by the humoral immune response

    Faez Amokrane Nait Mohamed, Daniel Lingwood
    It is proposed that innate immune cells are positioned to activate the naïve B cell repertoire and rational application of training stimuli could enforce this, offsetting original antigenic sin, wherein recall of ‘off-target’ B cell memory can obscure vaccine effectiveness.
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