Dopamine midbrain neurons surviving a lesion slowly recover their in vivo firing patterns by homeostatic pacemaker acceleration mediated by Kv4.3 channel downregulation.
Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light integration and behaviorally relevant vision.
Computational modeling of the memory modification process reveals biased internal states in an Alzheimer’s disease mouse model, providing a new approach for early cognitive assessment and diagnosis.
Optimal cue integration, Bayesian Causal Inference, spatial orienting, speech illusions and other key phenomena in audiovisual perception naturally emerge from the collective behavior of a population of Multisensory Correlation Detector.
Ion channel voltage-dependence alterations can shape intrinsic homeostatic plasticity, even if operating faster than other intrinsic regulatory processes—where timescale separation would suggest its influence should be negligible.
Full-length, autoinhibited LRRK2 assembles into distinct, shorter microtubule-bound filaments via a previously unobserved N-terminal repeat interface, revealing new structural states with potential therapeutic implications.
