Browse our latest Neuroscience articles

Page 135 of 609
    1. Neuroscience

    Circuit-based intervention corrects excessive dentate gyrus output in the fragile X mouse model

    Pan-Yue Deng, Ajeet Kumar ... Vitaly A Klyachko
    Circuit-based intervention corrects irreconcilable excitability defects between dentate granule cells and mossy cells in Fmr1 knockout mice, representing a promising strategy to restore the dentate excitation/inhibition balance and circuit computations.
    1. Neuroscience

    SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

    Surya Chandra Rao Thumu, Monika Jain ... Narendrakumar Ramanan
    Serum response factor (SRF) deficient reactive astrocytes are neuroprotective in the mammalian brain.
    1. Neuroscience

    Hearing: Letting the calcium flow

    Régis Nouvian
    Two calcium-binding proteins, CaBP1 and CaBP2, cooperate to keep calcium channels in the hair cells of the inner ear open.
    Version of Record
    Insight
    1. Cell Biology
    2. Neuroscience

    O-GlcNAc signaling increases neuron regeneration through one-carbon metabolism in Caenorhabditis elegans

    Dilip Kumar Yadav, Andrew C Chang ... Christopher V Gabel
    The specific metabolic pathways that increase neuron regeneration in ogt-1 mutant C. elegans following in vivo laser axotomy, highlighting the potential power for such metabolic targets in the treatment of neuronal injury.
    1. Neuroscience

    RatInABox, a toolkit for modelling locomotion and neuronal activity in continuous environments

    Tom M George, Mehul Rastogi ... Caswell Barry
    A new python package standardises and simplifies how spatial behaviour and neural representations are modelled in continuous environments.
    1. Neuroscience

    A spatial-attentional mechanism underlies action-related distortions of time judgment

    Liyu Cao
    The distribution of visuospatial attention shapes the timing report results obtained with the Libet clock method, thus explaining the temporal binding effect in this context.
    1. Neuroscience

    Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model

    Andrew S Blaeser, Jun Zhao ... Dan Levy
    Functional imaging of individual sensory afferents that innervate the cranial meninges in a mouse migraine model reveals heightened responsiveness to movement-related meningeal deformations that may underlie headache.
    1. Neuroscience

    RIM-BP2 regulates Ca2+ channel abundance and neurotransmitter release at hippocampal mossy fiber terminals

    Rinako Miyano, Hirokazu Sakamoto ... Takeshi Sakaba
    By combining direct presynaptic patch-clamp electrophysiology and super-resolution microscopy, it was found that KO of RIM-BP2 reduced calcium channel abundance in hippocampal mossy terminals.
    1. Neuroscience

    Differential interaction patterns of opioid analgesics with µ opioid receptors correlate with ligand-specific voltage sensitivity

    Sina B Kirchhofer, Victor Jun Yu Lim ... Moritz Bünemann
    The molecular pattern underlying the interactions of opioids with their receptor determines whether membrane depolarization increases or decreases their response or even convert antagonists to agonists.
    1. Genetics and Genomics
    2. Neuroscience

    Transcriptional cartography integrates multiscale biology of the human cortex

    Konrad Wagstyl, Sophie Adler ... Armin Raznahan
    An atlas of cortical expression for 20,781 genes in the adult human brain, validated against multiscale datasets, from neuroimaging measures of structure and function to molecular cell and layer markers.