Browse our latest Neuroscience articles

Page 187 of 608
    1. Neuroscience

    Hierarchical architecture of dopaminergic circuits enables second-order conditioning in Drosophila

    Daichi Yamada, Daniel Bushey ... Yoshinori Aso
    A slow and stable memory unit instructs fast and transient units by activating dopaminergic neurons via an excitatory hub interneuron connecting those units during second-order conditioning in Drosophila.
    1. Computational and Systems Biology
    2. Neuroscience

    A generalizable brain extraction net (BEN) for multimodal MRI data from rodents, nonhuman primates, and humans

    Ziqi Yu, Xiaoyang Han ... Jianfeng Feng
    The Brain Extraction Network (BEN) provides a robust, accurate, and generalizable solution not only for extracting brain tissue from multimodal MRI data in rodents, non-human primates, and humans, but also for improving the accuracy of downstream neuroimaging processing tasks.
    1. Cell Biology
    2. Neuroscience

    Protein composition of axonal dopamine release sites in the striatum

    Lauren Kershberg, Aditi Banerjee, Pascal S Kaeser
    Proximity proteomics combined with mouse genetics are used to assess the composition of active zone-like sites for dopamine release and reveal that the scaffolding protein RIM organizes these sites.
    1. Neuroscience

    Human and macaque pairs employ different coordination strategies in a transparent decision game

    Sebastian Moeller, Anton M Unakafov ... Igor Kagan
    Using novel approach to study real-time social interactions shows that mutual action visibility facilitates static and dynamic coordination in both species, but whereas humans employ dynamic turn-taking to equalize rewards, macaques, after training with a human, compete between themselves.
    1. Neuroscience

    Tracking multiple conformations occurring on angstrom-and-millisecond scales in single amino-acid-transporter molecules

    Yufeng Zhou, John H Lewis, Zhe Lu
    The present fluorescence polarization microscopy method enables the determination of the spatial orientations and lifetimes of a transporter protein in individual conformational states required for understanding the complex conformational mechanism underlying its function, applicable to investigation of other membrane proteins.
    1. Computational and Systems Biology
    2. Neuroscience

    Cellular composition and circuit organization of the locus coeruleus of adult mice

    Andrew McKinney, Ming Hu ... Xiaolong Jiang
    Interrogating mouse locus coeruleus via large-scale multipatch whole-cell recordings uncovers its cellular heterogeneity and cell-type-specific wiring logic.
    1. Neuroscience

    The tetraspanin TSPAN5 regulates AMPAR exocytosis by interacting with the AP4 complex

    Edoardo Moretto, Federico Miozzo ... Maria Passafaro
    In mature neurons, TSPAN5 assembles into a complex with AP4 and Stargazin to promote the exocytosis of AMPA receptors.
    1. Neuroscience
    2. Physics of Living Systems

    Scale-free behavioral dynamics directly linked with scale-free cortical dynamics

    Sabrina A Jones, Jacob H Barfield ... Woodrow L Shew
    Complex, multi-scale natural behaviors may arise from subpopulations of neurons in cerebral cortex operating near the tipping point of a phase transition, that is, near criticality.
    1. Neuroscience
    2. Genetics and Genomics

    Ecdysone acts through cortex glia to regulate sleep in Drosophila

    Yongjun Li, Paula Haynes ... Amita Sehgal
    Effects of ecdysone on sleep are mediated through lipid metabolism in cortex glia.
    1. Neuroscience

    Representational integration and differentiation in the human hippocampus following goal-directed navigation

    Corey Fernandez, Jiefeng Jiang ... Anthony D Wagner
    Mnemonic mechanisms of differentiation and integration within the medial temporal lobe occur concurrently during the learning of local and global environmental knowledge.