Michelle Jin, Simon O Ogundare ... Christine Ann Denny
A new scalable workflow for analyzing multiple ensemble datasets incorporates SMARTTR, an R package supporting network analysis, visualization, and the import of external datasets.
There is no discernible effect of an additional year of education from a policy change on long-term structural neuroimaging measures in a large aging sample (UK Biobank).
Aurore Thomazeau, Sabine Rannio ... Per Jesper Sjöström
Neocortical timing-dependent LTD relies on non-ionotropic presynaptic NMDA receptor signaling via JNK2, challenging the textbook view that NMDA receptors are ionotropic coincidence detectors in Hebbian plasticity.
Homotypic olfactory receptor neurons in Drosophila, including CO2-sensing neurons with distinctive sheet-like dendrites, exhibit unexpected morphological diversity that may underlie functional adaptability.
While persistent aggressive states in females are promoted by select cell types with recurrent connections (aIPg, pC1d+e), additional data and models are needed to explain the maintenance of these states.
Johanna Ganssauge, Sophie Hawkins ... Akshay Bhinge
A novel human iPSC-derived model induces mislocalization of endogenous TDP-43 without mutations or stress, recapitulating key ALS features including deficits in neuronal loss and morphology, splicing errors, and microRNA dysregulation.
The BRAIN Circuits Program of the NIH BRAIN Initiative has impacted how fundamental discovery in integrative systems neuroscience is investigated, commensurate with the complexity to address neurobehavioral and neurological dysfunctions.
