Post‑HI oxidative‑phosphorylation uncoupling drives secondary energy failure in neonatal brains, and preventing the post‑HI CMRO2 surge is a key mechanism underlying hypothermia’s neuroprotection.
R Sai Prathap Yadav, Paulami Dey ... Pavan Agrawal
A low-cost, portable platform combining machine learning–based classifiers enables accurate quantification of Drosophila aggression and courtship, expanding access to behavioral neuroscience in resource-limited settings.
Physical gel models and numerical simulations have been created to study ferret brain gyrification and cortical malformations, while comparisons with human phenotypes aim to link genetics and brain morphogenesis.
Louis Richevaux, Dongkyun Lim ... Desdemona Fricker
Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal compass.
A combination of viral strategies, electrophysiological methods, and behavioral tests reveals how GPR30 in spinal CCK+ neurons modulates neuropathic pain.
Roman Makarov, Spyridon Chavlis, Panayiota Poirazi
An interactive toolbox for standardizing, validating, simulating, reducing, and exploring detailed biophysical models that can be used to reveal how morpho-electric properties map to dendritic and neuronal outputs.