Browse our latest Neuroscience articles

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    1. Neuroscience

    Interacting rhythms enhance sensitivity of target detection in a fronto-parietal computational model of visual attention

    Amélie Aussel, Ian C Fiebelkorn ... Benjamin Rafael Pittman-Polletta
    A biophysical cortical circuit model reveals how thalamic inputs mediate complex dynamics in the frontal eye fields and lateral intraparietal area, enabling rhythmic enhancements in visual sensitivity observed behaviorally.
    1. Neuroscience

    Differential ripple propagation along the hippocampal longitudinal axis

    Roberto De Filippo, Dietmar Schmitz
    Ripple origination point shapes neural activity dynamics across the different hippocampal subfields.
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal tissue maturation of thalamocortical pathways in the human fetal brain

    Siân Wilson, Maximilian Pietsch ... Tomoki Arichi
    Using fetal magnetic resonance imaging (MRI), maturational changes in tissue microstructure can be derived using diffusion MRI which provide new insight into the fundamental neurobiological transitions occurring within the emerging thalamocortical white matter pathways.
    1. Neuroscience

    Rapid cell type-specific nascent proteome labeling in Drosophila

    Stefanny Villalobos-Cantor, Ruth M Barrett ... Ian Martin
    Newly-synthesized protein can be labeled with cellular specificity in Drosophila brain using the puromycin analog PhAc-OPP coupled to expression of the unblocking enzyme PGA in a tissue or cell type of interest.
    1. Neuroscience

    Functional cell types in the mouse superior colliculus

    Ya-tang Li, Markus Meister
    Neurons in the mouse superior colliculus comprise about 20 types based on their responses to visual stimuli, and neurons of the same type tend to cluster together.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly

    Martin H Berryer, Gizem Rizki ... Lindy E Barrett
    An automated synaptic phenotyping platform combined with small molecule screening reveals modulators of human neuron synapse formation.
    1. Neuroscience

    Aging and Spatial Navigation: When landmarks are not enough

    Paul F Hill
    Including geometric spatial cues in an environment can help reverse the difficulties with spatial navigation experienced by children and older adults.
    Version of Record
    Insight
    1. Neuroscience

    TIR-1/SARM1 inhibits axon regeneration and promotes axon degeneration

    Victoria L Czech, Lauren C O'Connor ... Alexandra B Byrne
    TIR-1 regulates both repair and destruction on either side of an injury axon.
    1. Neuroscience

    A task-general connectivity model reveals variation in convergence of cortical inputs to functional regions of the cerebellum

    Maedbh King, Ladan Shahshahani ... Jörn Diedrichsen
    Models of cortico-cerebellar connectivity are quantified using task-based fMRI, and demonstrate that convergent rather than sparse inputs best characterize cortico-cerebellar connectivity, namely, cerebellar areas linked to cognition receive the highest convergence of cortical inputs.
    1. Neuroscience

    TMS-evoked responses are driven by recurrent large-scale network dynamics

    Davide Momi, Zheng Wang, John D Griffiths
    Whole-brain computational modelling, incorporating novel ML-based parameter estimation techniques, reveals how transcranial magnetic stimulation-evoked brain responses are driven at earlier timepoints by local echoes of the external stimulus, and at later timepoints by large-scale network reverberation across the connectome.