Browse our latest Neuroscience articles

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    1. Neuroscience

    Fabry Disease: Ion channels and neuropathic pain

    Madeleine C Klein, Anne Louise Oaklander
    Pain behaviors in a Fabry mouse model are associated with the accumulation of a fat molecule that disrupts sodium ion channels in small fiber neurons.
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    1. Neuroscience

    Endocytosis at the Drosophila blood–brain barrier as a function for sleep

    Gregory Artiushin, Shirley L Zhang ... Amita Sehgal
    Endocytosis through the Drosophila blood–brain barrier influences and depends upon sleep.
    1. Neuroscience

    CA2 neuronal activity controls hippocampal low gamma and ripple oscillations

    Georgia M Alexander, Logan Y Brown ... Serena M Dudek
    Hippocampal area CA2 controls low gamma and ripple oscillations, brain waves known to be impaired in schizophrenia, implicating this important brain region in cognition.
    1. Neuroscience

    Molecular mechanisms that stabilize short term synaptic plasticity during presynaptic homeostatic plasticity

    Jennifer M Ortega, Özgür Genç, Graeme W Davis
    Genetic and electrophysiological experiments define how homeostatic signaling stabilizes both the gain and short-term dynamic properties of neurotransmitter release, ensuring that synaptic information transfer remains robust to external perturbation.
    1. Neuroscience

    Entrainment and maintenance of an internal metronome in supplementary motor area

    Jaime Cadena-Valencia, Otto García-Garibay ... Victor de Lafuente
    Temporal rhythms are encoded in the supplementary motor area by firing rate oscillations and rhythmic bursts of gamma-band LFP activity.
    1. Neuroscience

    Macro-connectomics and microstructure predict dynamic plasticity patterns in the non-human primate brain

    Sean Froudist-Walsh, Philip GF Browning ... Paula L Croxson
    Brain recovery after injury can be predicted based on its activity and structure, which may allow us to understand why some brain injuries lead to permanent loss of cognitive function, while others do not.
    1. Neuroscience

    Altered hippocampal interneuron activity precedes ictal onset

    Mitra L Miri, Martin Vinck ... Jessica A Cardin
    GABAergic interneuron populations in the hippocampus exhibit cell-type-specific patterns of disruption in advance of seizure onset.
    1. Cell Biology
    2. Neuroscience

    CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors

    Manuela D'Alessandro, Magali Richard ... Jean-Louis Bessereau
    The protein disulphide isomerase CRELD1 controls the biosynthesis of nicotinic acetylcholine receptors in nematode and mouse muscle.
    1. Neuroscience

    Bright multicolor labeling of neuronal circuits with fluorescent proteins and chemical tags

    Richi Sakaguchi, Marcus N Leiwe, Takeshi Imai
    A bright and stochastic multicolor labeling method, Tetbow, facilitates millimeters-scale reconstructions of neuronal circuits at a large scale using tissue clearing.
    1. Cell Biology
    2. Neuroscience

    Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones

    Nickolai V Vysokov, John-Paul Silva ... Yuri A Ushkaryov
    Lasso and latrophilin-1 interact across the synapse, while shed Lasso binds latrophilin-1 on distant growth cones and attracts them, providing a universal mechanism for short- and long-range axonal guidance.