In contrast to previous post-mortem or fixed tissue histochemical reports, live calcium and mitochondrial imaging data suggest that the enteric nervous system is not generally affected in Parkinson's disease patients.
An innovative inter-subject stimulus-locked brain activation approach uncovers marked topological differences in a brain network of higher-order visual regions in individuals with a congenital impairment in face recognition compared with controls.
An unbiased transcriptional profiling screen reveals the secreted matrix metalloproteinase MMP-1 is a transcriptional target of the ensheathing glial receptor Draper following acute axon injury in adult Drosophila.
Ivan Larderet, Pauline MJ Fritsch ... Simon G Sprecher
The synaptic connectome of the Drosophila larval visual circuit is the first case of a completely reconstructed visual network in a genetically fully tractable model organism.
James S Martenson, Tokiwa Yamasaki ... Susumu Tomita
A novel GABAAR assembly pathway that promotes synaptic inhibition is established and provides a molecular explanation for how GABAARs with distinct subunit compositions display distinct subcellular distributions.
The utility of split GFP for tissue-specific visualization of ribosomes in live Caenorhabditis elegans demonstrates the link between ribosomes and microtubules.
Michael R Bale, Malamati Bitzidou ... Miguel Maravall
Mice and humans learned to distinguish an arbitrary tactile sequence from other stimuli that differed only in their temporal patterning over hundreds of milliseconds, showing that sequence learning generalises across sensory modalities.
BalaT-dependent β-alanine trafficking pathway in retinal pigment cells is critical for maintaining synaptic transmission of photoreceptor neurons in Drosophila.
