Browse our latest Neuroscience articles

Page 484 of 599
    1. Neuroscience

    Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity

    Eiko Iwakoshi-Ukena, Kenshiro Shikano ... Kazuyoshi Ukena
    Neurosecretory protein GL, a previously unknown mammalian neuropeptide, is a novel hypothalamic factor which regulates feeding behavior and peripheral lipogenesis in animals.
    1. Neuroscience

    A connectome of a learning and memory center in the adult Drosophila brain

    Shin-ya Takemura, Yoshinori Aso ... Louis K Scheffer
    Connectomic analysis in the fly's (Drosophila) learning and memory center identifies unique circuit motifs that have not been anticipated by over 30 years of extensive anatomical, experimental and theoretical studies.
    1. Neuroscience

    Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

    Jordan G McCall, Edward R Siuda ... Michael R Bruchas
    Selective activation of locus coeruleus noradrenergic terminals drives anxiety-like behaviors through activation of β-adrenergic receptors in the basolateral amygdala.
    1. Neuroscience

    Motoneurons regulate the central pattern generator during drug-induced locomotor-like activity in the neonatal mouse

    Melanie Falgairolle, Joshua G Puhl ... Michael J O’Donovan
    Motoneuron activity provides feedback to the spinal network responsible for generating locomotion in the developing mouse spinal cord.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    A novel region in the CaV2.1 α1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

    Matthias Lübbert, R Oliver Goral ... Samuel M Young Jr
    A novel region in the CaV2.1 α1 subunit regulates coupling of synaptic vesicles to CaV2.1 calcium channels, synaptic vesicle release and docking, and the size of the fast and total releasable pools of synaptic vesicles.
    1. Neuroscience

    Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

    Nicole Scholz, Chonglin Guan ... Robert J Kittel
    Metabotropic mechanosensing occurs through an adhesion-type G protein-coupled receptor.
    1. Neuroscience

    Neurobehavioral evidence of interoceptive sensitivity in early infancy

    Lara Maister, Teresa Tang, Manos Tsakiris
    Pre-verbal infants demonstrate an implicit sensitivity to interoceptive sensations, which fluctuates spontaneously during emotional processing and guides audiovisual preferences in the environment.
    1. Neuroscience

    Sequential neuromodulation of Hebbian plasticity offers mechanism for effective reward-based navigation

    Zuzanna Brzosko, Sara Zannone ... Ole Paulsen
    Sequential neuromodulation by acetylcholine and dopamine enables correlational synaptic learning which, when incorporated into a computational model, yields effective navigation toward changing reward locations as in natural foraging behavior.
    1. Neuroscience

    Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation

    Anitha P Govind, Yolanda F Vallejo ... William N Green
    The smoking cessation drug varenicline (Chantix) and other weak base ligands reduce a4b2-type nicotinic receptor (a4b2R) upregulation through slow intracellular release due to selective trapping in acidic vesicles that contain a4b2Rs.
    1. Neuroscience

    A spiral attractor network drives rhythmic locomotion

    Angela M Bruno, William N Frost, Mark D Humphries
    The neural population of the Aplysia's pedal ganglion are a low-dimensional spiral attractor, and the parameters of the attractor directly define the properties of the Aplysia's escape locomotion behaviour.