Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Neuroscience

    Modeling the prodromal phase of Alzheimer’s disease: Selective amyloid-driven failure of cholinergic medial septal neurons perturbs REM sleep, cognition, emotion, and broadcasts pathology in aging mice

    Mathieu Nollet, Wei Ba ... William Wisden
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Synergistic Inhibition of Notch Signaling and Forced Cell Cycle Re-entry Drive Müller Glia Reprogramming in Uninjured Mouse Retina

    Baoshan Liao, Chengshang Lyu ... Wenjun Xiong
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    Zasp52’s differentially expressed intrinsically disordered region confers thin filament stability at the Z-disc

    Nikolai Ho, Frieder Schöck
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Tatton-Brown-Rahman Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

    Gareth Chapman, Julianna J Determan ... Kristen L Kroll
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    A simplified and highly efficient cell-free protein synthesis system for prokaryotes

    Xianshengjie Lang, Changbin Zhang ... Wenfei Li
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Synthetic auxotrophy reveals metabolic regulation of plasma cell generation, affinity maturation, and cytokine receptor signaling

    Sung Hoon Cho, Shawna K Brookens ... Mark R Boothby
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    A single evidence accumulation process informs perceptual choices and subsequent confidence reports

    John P Grogan, Luc Vermeylen ... Redmond G O’Connell
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Sequential and coordinated control of human plasma cell differentiation by IRF4 and BLIMP1 utilizing a discriminating ISRE/EICE motif lexicon

    Louis C Lau, Sneha Lal ... Harinder Singh
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    Molecular mechanisms underlying the prepupal-instar-forming metamorphosis in black soldier fly (Hermetia illucens)

    Lingtao Zhang, Masami Shimoda, Chieka Minakuchi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    cuBNM: GPU-Accelerated Brain Network Modeling

    Amin Saberi, Bin Wan ... Sofie L Valk
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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