Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Neuroscience

    Establishing synthetic ribbon-type active zones in a heterologous expression system

    Rohan Kapoor, Thanh Thao Do ... Tobias Moser
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    A Novel Mouse Model for LAMA2-Related Muscular Dystrophy: Analysis of Molecular Pathogenesis and Clinical Phenotype

    Dandan Tan, Yidan Liu ... Hui Xiong
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes

    Vikram Dalal, Brandon K Tan ... Wayland WL Cheng
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Perinatal environmental enrichment affects murine neonates’ brain structure before their active engagement with environment

    Malte S Kaller, Clémence Ligneul ... Jason P Lerch
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease

    Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection

    Dayeon Lee, Sin Young Choi ... Jihwan Park
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Online reinforcement learning of state representation in recurrent network: the power of random feedback and biological constraints

    Takayuki Tsurumi, Ayaka Kato ... Kenji Morita
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Ancient Trans-Species Polymorphism at the Major Histocompatibility Complex in Primates

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathology

    Kelsey M Nemec, Genevieve Uy ... F Chris Bennett
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Exceptional
    1. Neuroscience

    On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy

    Yuzhang Chen, Brian Litt ... Hajime Takano
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid