Reviewed Preprints

Preprints that have been invited for review by eLife are published as Reviewed Preprints and include an eLife assessment, public reviews and a response from the authors (if available).

Latest

    1. Cell Biology
    2. Chromosomes and Gene Expression

    The nuclear membrane protein Samp1 links peripheral genome organization to the myogenic transcriptional program

    Urška Kašnik, Irene Mei ... Einar Hallberg
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Single-Molecule Nanopore Profiling of p53-TAD’s Conformational Dynamics, Interactions, and Inhibition

    David DeCoeur, Samantha Schultz ... Min Chen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Compelling
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Dynamin 2–dependent endocytosis differentially regulates ligand and receptor contributions to Notch signaling during neural precursor cell fate determination

    Joshua J Breunig, Jon I Arellano ... Pasko Rakic
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression

    KMT2A modulates the epigenetic landscape of rDNA by facilitating the recruitment of histone lysine acetyltransferase PCAF to the rDNA locus

    Kaisar Ahmad Lone, Anita Choudhary ... Shweta Tyagi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Integrin-dependent trafficking of CD98hc reduces endocytic noise to maintain metabolic homeostasis

    F Sila Rizalar, Hans Peter Grimm ... Roberto Villaseñor
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease
    2. Computational and Systems Biology

    High-dimensional Characterization of Genome–Environment Fitness Landscapes in Klebsiella pneumoniae

    Ge Zhou, Georgia Williams ... Danesh Moradigaravand
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Plant Biology

    Multi-omic integration using interpretable machine learning reveals genetic mechanisms of trait variation and phenotypic plasticity in switchgrass

    Paulo Izquierdo, Xiaoyu Weng ... Shin-Han Shiu
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Kinesin-1 holoenzyme assembly coordinates cargo-adaptor recognition with heavy-chain autoinhibition

    Jingling Niu, Mengmeng Zhang ... Chao Wang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Global Nernstian astrocytic depolarization breaks down during local synaptic input

    Ryo J Nakatani, Erik De Schutter
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Congruent neuronal modulation across competing actions challenges the role of the substantia nigra in action selection

    Lingfeng Hou, Derin Timuçin ... John Assad
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Solid
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